Oxidized LDL induces FAK-dependent RSK signaling to drive NF-&#954;B activation and VCAM-1 expression.

Yurdagul, Arif; Sulzmaier, Florian J; Chen, Xiao L; Pattillo, Christopher B; Schlaepfer, David D; Orr, A Wayne

Oxidized LDL induces FAK-dependent RSK signaling to drive NF-κB activation and VCAM-1 expression.

Yurdagul, Arif; Sulzmaier, Florian J; Chen, Xiao L; Pattillo, Christopher B; Schlaepfer, David D; Orr, A Wayne.

Yurdagul A; Department of Pathology and Translational Pathobiology, LSU Health Sciences Center, Shreveport, LA 71130, USA Department of Cell Biology and Anatomy, LSU Health Sciences Center, Shreveport, LA 71130, USA.
Sulzmaier FJ; UCSD San Diego, Moores Cancer Center, Department of Reproductive Medicine, 0803 3855 Health Sciences Dr., La Jolla, CA 92093, USA.
Chen XL; UCSD San Diego, Moores Cancer Center, Department of Reproductive Medicine, 0803 3855 Health Sciences Dr., La Jolla, CA 92093, USA State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, Fujian 361102, China.
Pattillo CB; Department of Cellular and Molecular Physiology, LSU Health Sciences Center, Shreveport, LA 71130, USA.
Schlaepfer DD; UCSD San Diego, Moores Cancer Center, Department of Reproductive Medicine, 0803 3855 Health Sciences Dr., La Jolla, CA 92093, USA.
Orr AW; Department of Pathology and Translational Pathobiology, LSU Health Sciences Center, Shreveport, LA 71130, USA Department of Cell Biology and Anatomy, LSU Health Sciences Center, Shreveport, LA 71130, USA aorr@lsuhsc.edu.

J Cell Sci ; 129(8): 1580-91, 2016 Apr 15.

Article en En | MEDLINE | ID: mdl-26906414

Asunto(s)

Aterosclerosis/metabolismo; Células Endoteliales/fisiología; Quinasa 1 de Adhesión Focal/metabolismo; Quinasa I-kappa B/metabolismo; Lipoproteínas LDL/metabolismo; FN-kappa B/metabolismo; Molécula 1 de Adhesión Celular Vascular/metabolismo; Animales; Adhesión Celular; Quinasa 1 de Adhesión Focal/genética; Regulación de la Expresión Génica; Células HEK293; Humanos; Quinasa I-kappa B/genética; Macrófagos/fisiología; Ratones; Ratones Endogámicos C57BL; Ratones Transgénicos; FN-kappa B/genética; Proteínas Quinasas S6 Ribosómicas 90-kDa/metabolismo; Transducción de Señal; Molécula 1 de Adhesión Celular Vascular/genética

Palabras clave

Atherosclerosis; FAK; Focal adhesion kinase; NF-κB; Nuclear factor κB; OxLDL; Oxidized LDL; RSK; Ribosomal S6 kinase

Texto completo

Imprimir

XML

PubMed Links

Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: FN-kappa B / Molécula 1 de Adhesión Celular Vascular / Células Endoteliales / Aterosclerosis / Quinasa I-kappa B / Quinasa 1 de Adhesión Focal / Lipoproteínas LDL Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2016 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Search on Google