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Reduction of ciliary length through pharmacologic or genetic inhibition of CDK5 attenuates polycystic kidney disease in a model of nephronophthisis.
Husson, Hervé; Moreno, Sarah; Smith, Laurie A; Smith, Mandy M; Russo, Ryan J; Pitstick, Rose; Sergeev, Mikhail; Ledbetter, Steven R; Bukanov, Nikolay O; Lane, Monica; Zhang, Kate; Billot, Katy; Carlson, George; Shah, Jagesh; Meijer, Laurent; Beier, David R; Ibraghimov-Beskrovnaya, Oxana.
  • Husson H; Department of Rare Diseases, Sanofi-Genzyme R&D Center, 49 New York Avenue, Framingham, MA 01701, USA.
  • Moreno S; Department of Rare Diseases, Sanofi-Genzyme R&D Center, 49 New York Avenue, Framingham, MA 01701, USA.
  • Smith LA; Department of Rare Diseases, Sanofi-Genzyme R&D Center, 49 New York Avenue, Framingham, MA 01701, USA.
  • Smith MM; Department of Rare Diseases, Sanofi-Genzyme R&D Center, 49 New York Avenue, Framingham, MA 01701, USA.
  • Russo RJ; Department of Rare Diseases, Sanofi-Genzyme R&D Center, 49 New York Avenue, Framingham, MA 01701, USA.
  • Pitstick R; McLaughlin Research Institute, 1520 23rd Street South, Great Falls, Montana 59405, USA.
  • Sergeev M; Harvard Institutes of Medicine, 4 Blackfan Circle HIM568, Boston, MA 02115, USA.
  • Ledbetter SR; Department of Rare Diseases, Sanofi-Genzyme R&D Center, 49 New York Avenue, Framingham, MA 01701, USA.
  • Bukanov NO; Department of Rare Diseases, Sanofi-Genzyme R&D Center, 49 New York Avenue, Framingham, MA 01701, USA.
  • Lane M; Department of Biological Mass Spectrometry & Biomarker Research, Sanofi-Genzyme R&D Center, 1 Mountain Road, Framingham, MA 01701, USA.
  • Zhang K; Department of Biological Mass Spectrometry & Biomarker Research, Sanofi-Genzyme R&D Center, 1 Mountain Road, Framingham, MA 01701, USA.
  • Billot K; ManRos Therapeutics, Hotel de Recherche-Centre de Perharidy, 29680 Roscoff, France.
  • Carlson G; McLaughlin Research Institute, 1520 23rd Street South, Great Falls, Montana 59405, USA.
  • Shah J; Harvard Institutes of Medicine, 4 Blackfan Circle HIM568, Boston, MA 02115, USA.
  • Meijer L; ManRos Therapeutics, Hotel de Recherche-Centre de Perharidy, 29680 Roscoff, France.
  • Beier DR; Center for Developmental Biology and Regenerative Medicine, Seattle Children's Research Institute, 1900 9th Avenue, Seattle, WA 98101, USA.
  • Ibraghimov-Beskrovnaya O; Department of Rare Diseases, Sanofi-Genzyme R&D Center, 49 New York Avenue, Framingham, MA 01701, USA oxana.beskrovnaya@genzyme.com.
Hum Mol Genet ; 25(11): 2245-2255, 2016 06 01.
Article en En | MEDLINE | ID: mdl-27053712
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cilios / Quinasa 5 Dependiente de la Ciclina / Fallo Renal Crónico / Enfermedades Renales Poliquísticas Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2016 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cilios / Quinasa 5 Dependiente de la Ciclina / Fallo Renal Crónico / Enfermedades Renales Poliquísticas Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2016 Tipo del documento: Article