Multifaceted Histone H3 Methylation and Phosphorylation Readout by the Plant Homeodomain Finger of Human Nuclear Antigen Sp100C.

Zhang, Xiaojie; Zhao, Dan; Xiong, Xiaozhe; He, Zhimin; Li, Haitao

Zhang, Xiaojie; Zhao, Dan; Xiong, Xiaozhe; He, Zhimin; Li, Haitao.

Zhang X; From the Ministry of Education Key Laboratory of Protein Sciences, Beijing Advanced Innovation Center for Structural Biology, Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing 100084 and.
Zhao D; From the Ministry of Education Key Laboratory of Protein Sciences, Beijing Advanced Innovation Center for Structural Biology, Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing 100084 and.
Xiong X; From the Ministry of Education Key Laboratory of Protein Sciences, Beijing Advanced Innovation Center for Structural Biology, Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing 100084 and.
He Z; From the Ministry of Education Key Laboratory of Protein Sciences, Beijing Advanced Innovation Center for Structural Biology, Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing 100084 and.
Li H; From the Ministry of Education Key Laboratory of Protein Sciences, Beijing Advanced Innovation Center for Structural Biology, Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing 100084 and; the Collaborative Innovation Center for Biotherapy, West China Hospital, Si

J Biol Chem ; 291(24): 12786-12798, 2016 Jun 10.

Article en En | MEDLINE | ID: mdl-27129259

Asunto(s)

Antígenos Nucleares/metabolismo; Autoantígenos/metabolismo; Histonas/metabolismo; Lisina/metabolismo; Secuencia de Aminoácidos; Antígenos Nucleares/química; Antígenos Nucleares/genética; Autoantígenos/química; Autoantígenos/genética; Sitios de Unión/genética; Calorimetría/métodos; Cristalografía por Rayos X; Células HeLa; Histonas/química; Humanos; Enlace de Hidrógeno; Lisina/química; Metilación; Microscopía Confocal; Modelos Moleculares; Mutación; Fosforilación; Unión Proteica; Dominios Proteicos; Isoformas de Proteínas/química; Isoformas de Proteínas/genética; Isoformas de Proteínas/metabolismo; Homología de Secuencia de Aminoácido

Palabras clave

H3T3 phosphorylation; PHD finger; Sp100C; autoimmune disease; crystal structure; epigenetics; histone modification; nuclear body protein

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Autoantígenos / Histonas / Antígenos Nucleares / Lisina Límite: Humans Idioma: En Año: 2016 Tipo del documento: Article

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