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Viable RNaseH1 knockout mice show RNaseH1 is essential for R loop processing, mitochondrial and liver function.
Lima, Walt F; Murray, Heather M; Damle, Sagar S; Hart, Christopher E; Hung, Gene; De Hoyos, Cheryl Li; Liang, Xue-Hai; Crooke, Stanley T.
  • Lima WF; Department of Core Antisense Research, Ionis Pharmaceuticals Inc., 2855 Gazelle Court, Carlsbad, CA 92010, USA.
  • Murray HM; Department of Core Antisense Research, Ionis Pharmaceuticals Inc., 2855 Gazelle Court, Carlsbad, CA 92010, USA.
  • Damle SS; Department of Functional Genomics, Ionis Pharmaceuticals Inc., 2855 Gazelle Court, Carlsbad, CA 92010, USA.
  • Hart CE; Department of Functional Genomics, Ionis Pharmaceuticals Inc., 2855 Gazelle Court, Carlsbad, CA 92010, USA.
  • Hung G; Department of Antisense Drug Discovery, Ionis Pharmaceuticals Inc., 2855 Gazelle Court, Carlsbad, CA 92010, USA.
  • De Hoyos CL; Department of Core Antisense Research, Ionis Pharmaceuticals Inc., 2855 Gazelle Court, Carlsbad, CA 92010, USA.
  • Liang XH; Department of Core Antisense Research, Ionis Pharmaceuticals Inc., 2855 Gazelle Court, Carlsbad, CA 92010, USA.
  • Crooke ST; Department of Core Antisense Research, Ionis Pharmaceuticals Inc., 2855 Gazelle Court, Carlsbad, CA 92010, USA scrooke@ionisph.com.
Nucleic Acids Res ; 44(11): 5299-312, 2016 06 20.
Article en En | MEDLINE | ID: mdl-27131367

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: ARN / Mitocondrias Hepáticas / Ribonucleasa H / Hígado / Conformación de Ácido Nucleico Límite: Animals Idioma: En Año: 2016 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: ARN / Mitocondrias Hepáticas / Ribonucleasa H / Hígado / Conformación de Ácido Nucleico Límite: Animals Idioma: En Año: 2016 Tipo del documento: Article