Evaluation of in-vitro cytotoxicity and cellular uptake efficiency of zidovudine-loaded solid lipid nanoparticles modified with Aloe Vera in glioma cells.

K S, Joshy; Sharma, Chandra P; Kalarikkal, Nandakumar; Sandeep, K; Thomas, Sabu; Pothen, Laly A

K S, Joshy; Sharma, Chandra P; Kalarikkal, Nandakumar; Sandeep, K; Thomas, Sabu; Pothen, Laly A.

K S J; Department of Chemistry, CMS College Kottayam, Kerala, India; International and Inter University Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam 686 560, Kerala, India.
Sharma CP; Division of Biosurface Technology, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Science and Technology, Poojappura, Thiruvananthapuram, Kerala, India.
Kalarikkal N; International and Inter University Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam 686 560, Kerala, India; School of Pure and Applied Physics, Mahatma Gandhi University, Kottayam 686 560, Kerala, India.
Sandeep K; International and Inter University Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam 686 560, Kerala, India.
Thomas S; International and Inter University Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam 686 560, Kerala, India; School of Chemical Sciences, Mahatma Gandhi University, Kottayam 686 560, Kerala, India. Electronic address: sabuchathukulam@yahoo.co.uk.
Pothen LA; Department of Chemistry, Bishop Moore College, Mavelikkara, Kerala, India.

Mater Sci Eng C Mater Biol Appl ; 66: 40-50, 2016 Sep 01.

Article en En | MEDLINE | ID: mdl-27207037

Asunto(s)

Aloe/química; Nanopartículas/química; Zidovudina/química; Aloe/metabolismo; Antineoplásicos/química; Antineoplásicos/farmacología; Línea Celular Tumoral; Supervivencia Celular/efectos de los fármacos; Portadores de Fármacos/química; Composición de Medicamentos; Liberación de Fármacos; Dispersión Dinámica de Luz; Hemólisis/efectos de los fármacos; Humanos; Lípidos/química; Microscopía Electrónica de Transmisión; Microscopía Fluorescente; Tamaño de la Partícula; Espectroscopía Infrarroja por Transformada de Fourier; Zidovudina/farmacología

Palabras clave

Aloe Vera; Blood compatibility; Cytotoxicity; Uptake; Zidovudine

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Zidovudina / Aloe / Nanopartículas Límite: Humans Idioma: En Año: 2016 Tipo del documento: Article

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Zidovudina / Aloe / Nanopartículas Límite: Humans Idioma: En Año: 2016 Tipo del documento: Article