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Inhibition of FGF/FGFR autocrine signaling in mesothelioma with the FGF ligand trap, FP-1039/GSK3052230.
Blackwell, Christina; Sherk, Christian; Fricko, Maggie; Ganji, Gopinath; Barnette, Mary; Hoang, Bao; Tunstead, James; Skedzielewski, Tina; Alsaid, Hasan; Jucker, Beat M; Minthorn, Elisabeth; Kumar, Rakesh; DeYoung, M Phillip.
  • Blackwell C; Oncology R&D, GlaxoSmithKline Research and Development, Collegeville, PA 19426, USA.
  • Sherk C; Oncology R&D, GlaxoSmithKline Research and Development, Collegeville, PA 19426, USA.
  • Fricko M; Oncology R&D, GlaxoSmithKline Research and Development, Collegeville, PA 19426, USA.
  • Ganji G; Oncology R&D, GlaxoSmithKline Research and Development, Collegeville, PA 19426, USA.
  • Barnette M; Oncology R&D, GlaxoSmithKline Research and Development, Collegeville, PA 19426, USA.
  • Hoang B; Platform Technology and Science, GlaxoSmithKline Research and Development, King of Prussia, PA 19406, USA.
  • Tunstead J; Platform Technology and Science, GlaxoSmithKline Research and Development, King of Prussia, PA 19406, USA.
  • Skedzielewski T; Platform Technology and Science, GlaxoSmithKline Research and Development, King of Prussia, PA 19406, USA.
  • Alsaid H; Platform Technology and Science, GlaxoSmithKline Research and Development, King of Prussia, PA 19406, USA.
  • Jucker BM; Platform Technology and Science, GlaxoSmithKline Research and Development, King of Prussia, PA 19406, USA.
  • Minthorn E; Oncology R&D, GlaxoSmithKline Research and Development, Collegeville, PA 19426, USA.
  • Kumar R; Oncology R&D, GlaxoSmithKline Research and Development, Collegeville, PA 19426, USA.
  • DeYoung MP; Oncology R&D, GlaxoSmithKline Research and Development, Collegeville, PA 19426, USA.
Oncotarget ; 7(26): 39861-39871, 2016 Jun 28.
Article en En | MEDLINE | ID: mdl-27223434

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Receptor Tipo 1 de Factor de Crecimiento de Fibroblastos / Factores de Crecimiento de Fibroblastos / Mesotelioma Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Año: 2016 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Receptor Tipo 1 de Factor de Crecimiento de Fibroblastos / Factores de Crecimiento de Fibroblastos / Mesotelioma Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Año: 2016 Tipo del documento: Article