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Dual TORK/DNA-PK inhibition blocks critical signaling pathways in chronic lymphocytic leukemia.
Thijssen, Rachel; Ter Burg, Johanna; Garrick, Brett; van Bochove, Gregor G W; Brown, Jennifer R; Fernandes, Stacey M; Rodríguez, María Solé; Michot, Jean-Marie; Hallek, Michael; Eichhorst, Barbara; Reinhardt, Hans Christian; Bendell, Johanna; Derks, Ingrid A M; van Kampen, Roel J W; Hege, Kristen; Kersten, Marie José; Trowe, Torsten; Filvaroff, Ellen H; Eldering, Eric; Kater, Arnon P.
  • Thijssen R; Department of Experimental Immunology and Department of Hematology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands;
  • Ter Burg J; Department of Experimental Immunology and Department of Hematology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands;
  • Garrick B; Celgene, San Francisco, CA;
  • van Bochove GG; Department of Experimental Immunology and Department of Hematology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands;
  • Brown JR; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA;
  • Fernandes SM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA;
  • Rodríguez MS; Department of Hematology, Hospital Universitario Virgen del Rocío, Seville, Spain;
  • Michot JM; Department of Hematology, Institut Gustave Roussy, Villejuif, France;
  • Hallek M; Department of Hematology, University Hospital, Cologne, Germany;
  • Eichhorst B; Department of Hematology, University Hospital, Cologne, Germany;
  • Reinhardt HC; Department of Hematology, University Hospital, Cologne, Germany;
  • Bendell J; Sarah Cannon Research Institute/Tennessee Oncology, Nashville, TN;
  • Derks IA; Department of Experimental Immunology and.
  • van Kampen RJ; Orbis Medisch Centrum, Sittard, The Netherlands; and.
  • Hege K; Celgene, San Francisco, CA;
  • Kersten MJ; Department of Hematology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Lymphoma and Myeloma Center Amsterdam, The Netherlands.
  • Trowe T; Celgene, San Francisco, CA;
  • Filvaroff EH; Celgene, San Francisco, CA;
  • Eldering E; Department of Experimental Immunology and Lymphoma and Myeloma Center Amsterdam, The Netherlands.
  • Kater AP; Department of Hematology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Lymphoma and Myeloma Center Amsterdam, The Netherlands.
Blood ; 128(4): 574-83, 2016 07 28.
Article en En | MEDLINE | ID: mdl-27235137
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pirazinas / Triazoles / Proteínas Nucleares / Leucemia Linfocítica Crónica de Células B / Resistencia a Antineoplásicos / Proteína Quinasa Activada por ADN / Serina-Treonina Quinasas TOR / Proteínas de Neoplasias Límite: Female / Humans / Male Idioma: En Año: 2016 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pirazinas / Triazoles / Proteínas Nucleares / Leucemia Linfocítica Crónica de Células B / Resistencia a Antineoplásicos / Proteína Quinasa Activada por ADN / Serina-Treonina Quinasas TOR / Proteínas de Neoplasias Límite: Female / Humans / Male Idioma: En Año: 2016 Tipo del documento: Article