XPA: A key scaffold for human nucleotide excision repair.
DNA Repair (Amst)
; 44: 123-135, 2016 08.
Article
en En
| MEDLINE
| ID: mdl-27247238
ABSTRACT
Nucleotide excision repair (NER) is essential for removing many types of DNA lesions from the genome, yet the mechanisms of NER in humans remain poorly understood. This review summarizes our current understanding of the structure, biochemistry, interaction partners, mechanisms, and disease-associated mutations of one of the critical NER proteins, XPA.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Xerodermia Pigmentosa
/
ADN
/
Reparación del ADN
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Proteína de la Xerodermia Pigmentosa del Grupo A
Límite:
Animals
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Humans
Idioma:
En
Año:
2016
Tipo del documento:
Article