Loss of miR-1258 contributes to carcinogenesis and progression of liver cancer through targeting CDC28 protein kinase regulatory subunit 1B.

Hu, Minghua; Wang, Mingwei; Lu, Huihong; Wang, Xiaoming; Fang, Xiaoshan; Wang, Jinguo; Ma, Chenyang; Chen, Xiaobing; Xia, Hongping

Hu, Minghua; Wang, Mingwei; Lu, Huihong; Wang, Xiaoming; Fang, Xiaoshan; Wang, Jinguo; Ma, Chenyang; Chen, Xiaobing; Xia, Hongping.

Hu M; Department of Hepatobiliary Surgery, Affiliated Yijishan Hospital of Wannan Medical College, Wuhu, 241001, China.
Wang M; Division of Cardiovascular Medicine, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, 310015, China.
Lu H; Department of Anesthesiology, East Hospital, Tongji University School of Medicine, Shanghai, 200120, China.
Wang X; Department of Hepatobiliary Surgery, Affiliated Yijishan Hospital of Wannan Medical College, Wuhu, 241001, China.
Fang X; Department of Hepatobiliary Surgery, Affiliated Yijishan Hospital of Wannan Medical College, Wuhu, 241001, China.
Wang J; Department of Hepatobiliary Surgery, Affiliated Yijishan Hospital of Wannan Medical College, Wuhu, 241001, China.
Ma C; Department of Hepatobiliary Surgery, Affiliated Yijishan Hospital of Wannan Medical College, Wuhu, 241001, China.
Chen X; Department of Oncology, The Affiliated Cancer Hospital, Zhengzhou University, Zhengzhou, 450008, China.
Xia H; Department of Hepatobiliary Surgery, Affiliated Yijishan Hospital of Wannan Medical College, Wuhu, 241001, China.

Oncotarget ; 7(28): 43419-43431, 2016 Jul 12.

Article en En | MEDLINE | ID: mdl-27270326

Asunto(s)

Quinasas CDC2-CDC28/genética; Carcinogénesis/genética; Carcinoma Hepatocelular/genética; Regulación Neoplásica de la Expresión Génica; Neoplasias Hepáticas/genética; MicroARNs/metabolismo; Animales; Antibióticos Antineoplásicos/uso terapéutico; Apoptosis/genética; Biomarcadores de Tumor/metabolismo; Quinasas CDC2-CDC28/metabolismo; Carcinoma Hepatocelular/tratamiento farmacológico; Carcinoma Hepatocelular/mortalidad; Carcinoma Hepatocelular/patología; Línea Celular Tumoral; Movimiento Celular; Proliferación Celular; Transformación Celular Neoplásica; Progresión de la Enfermedad; Supervivencia sin Enfermedad; Regulación hacia Abajo; Doxorrubicina/uso terapéutico; Citometría de Flujo; Puntos de Control de la Fase G1 del Ciclo Celular/genética; Humanos; Etiquetado Corte-Fin in Situ; Hígado/patología; Neoplasias Hepáticas/tratamiento farmacológico; Neoplasias Hepáticas/mortalidad; Neoplasias Hepáticas/patología; Masculino; Ratones; Ratones Endogámicos BALB C; Ratones Desnudos; Ensayos Antitumor por Modelo de Xenoinjerto

Palabras clave

CKS1B; liver cancer; miR-1258; recurrence; stemness

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Regulación Neoplásica de la Expresión Génica / Carcinoma Hepatocelular / MicroARNs / Quinasas CDC2-CDC28 / Carcinogénesis / Neoplasias Hepáticas Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Año: 2016 Tipo del documento: Article

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