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A novel approach to detect resistance mechanisms reveals FGR as a factor mediating HDAC inhibitor SAHA resistance in B-cell lymphoma.
Joosten, Maria; Ginzel, Sebastian; Blex, Christian; Schmidt, Dmitri; Gombert, Michael; Chen, Cai; Linka, René Martin; Gräbner, Olivia; Hain, Anika; Hirsch, Burkhard; Sommerfeld, Anke; Seegebarth, Anke; Gruber, Uschi; Maneck, Corinna; Zhang, Langhui; Stenin, Katharina; Dieks, Henrik; Sefkow, Michael; Münk, Carsten; Baldus, Claudia D; Thiele, Ralf; Borkhardt, Arndt; Hummel, Michael; Köster, Hubert; Fischer, Ute; Dreger, Mathias; Seitz, Volkhard.
  • Joosten M; Institute of Pathology, Charité University Medicine, Campus Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, Germany.
  • Ginzel S; Department of Pediatric Oncology, Hematology and Clinical Immunology, Center of Child and Adolescent Health, Medical Faculty, Heinrich-Heine-University, Moorenstr. 5, 40225 Düsseldorf, Germany; Department of Computer Science, Bonn-Rhine-Sieg University of Applied Sciences, Grantham-Allee 20, 53757 S
  • Blex C; caprotec bioanalytics GmbH, Magnusstraße 11, 12489 Berlin, Germany.
  • Schmidt D; caprotec bioanalytics GmbH, Magnusstraße 11, 12489 Berlin, Germany.
  • Gombert M; Department of Pediatric Oncology, Hematology and Clinical Immunology, Center of Child and Adolescent Health, Medical Faculty, Heinrich-Heine-University, Moorenstr. 5, 40225 Düsseldorf, Germany.
  • Chen C; Department of Pediatric Oncology, Hematology and Clinical Immunology, Center of Child and Adolescent Health, Medical Faculty, Heinrich-Heine-University, Moorenstr. 5, 40225 Düsseldorf, Germany.
  • Linka RM; Department of Pediatric Oncology, Hematology and Clinical Immunology, Center of Child and Adolescent Health, Medical Faculty, Heinrich-Heine-University, Moorenstr. 5, 40225 Düsseldorf, Germany.
  • Gräbner O; caprotec bioanalytics GmbH, Magnusstraße 11, 12489 Berlin, Germany.
  • Hain A; Clinic for Gastroenterology, Hepatology and Infectiology, Medical Faculty, Heinrich-Heine-University, Moorenstrasse 5, 40225 Düsseldorf, Germany.
  • Hirsch B; Institute of Pathology, Charité University Medicine, Campus Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, Germany.
  • Sommerfeld A; Institute of Pathology, Charité University Medicine, Campus Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, Germany.
  • Seegebarth A; Institute of Pathology, Charité University Medicine, Campus Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, Germany.
  • Gruber U; caprotec bioanalytics GmbH, Magnusstraße 11, 12489 Berlin, Germany.
  • Maneck C; caprotec bioanalytics GmbH, Magnusstraße 11, 12489 Berlin, Germany.
  • Zhang L; Department of Pediatric Oncology, Hematology and Clinical Immunology, Center of Child and Adolescent Health, Medical Faculty, Heinrich-Heine-University, Moorenstr. 5, 40225 Düsseldorf, Germany; Department of Hematology, Union Hospital, Fujian Medical University, NO.29,Xinquan Road, Fuzhou City, Fuji
  • Stenin K; caprotec bioanalytics GmbH, Magnusstraße 11, 12489 Berlin, Germany.
  • Dieks H; caprotec bioanalytics GmbH, Magnusstraße 11, 12489 Berlin, Germany.
  • Sefkow M; caprotec bioanalytics GmbH, Magnusstraße 11, 12489 Berlin, Germany.
  • Münk C; Clinic for Gastroenterology, Hepatology and Infectiology, Medical Faculty, Heinrich-Heine-University, Moorenstrasse 5, 40225 Düsseldorf, Germany.
  • Baldus CD; Department of Hematology and Oncology, Charité University Medicine, Campus Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, Germany.
  • Thiele R; Department of Computer Science, Bonn-Rhine-Sieg University of Applied Sciences, Grantham-Allee 20, 53757 Sankt Augustin, Germany.
  • Borkhardt A; Department of Pediatric Oncology, Hematology and Clinical Immunology, Center of Child and Adolescent Health, Medical Faculty, Heinrich-Heine-University, Moorenstr. 5, 40225 Düsseldorf, Germany.
  • Hummel M; Institute of Pathology, Charité University Medicine, Campus Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, Germany.
  • Köster H; caprotec bioanalytics GmbH, Magnusstraße 11, 12489 Berlin, Germany.
  • Fischer U; Department of Pediatric Oncology, Hematology and Clinical Immunology, Center of Child and Adolescent Health, Medical Faculty, Heinrich-Heine-University, Moorenstr. 5, 40225 Düsseldorf, Germany.
  • Dreger M; caprotec bioanalytics GmbH, Magnusstraße 11, 12489 Berlin, Germany.
  • Seitz V; Institute of Pathology, Charité University Medicine, Campus Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, Germany. Electronic address: volkhard.seitz@charite.de.
Mol Oncol ; 10(8): 1232-44, 2016 10.
Article en En | MEDLINE | ID: mdl-27324824
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Linfoma de Células B / Proteínas Proto-Oncogénicas / Familia-src Quinasas / Resistencia a Antineoplásicos / Inhibidores de Histona Desacetilasas / Ácidos Hidroxámicos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2016 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Linfoma de Células B / Proteínas Proto-Oncogénicas / Familia-src Quinasas / Resistencia a Antineoplásicos / Inhibidores de Histona Desacetilasas / Ácidos Hidroxámicos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2016 Tipo del documento: Article