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An immunogen containing four tandem 10E8 epitope repeats with exposed key residues induces antibodies that neutralize HIV-1 and activates an ADCC reporter gene.
Sun, Zhiwu; Zhu, Yun; Wang, Qian; Ye, Ling; Dai, Yanyan; Su, Shan; Yu, Fei; Ying, Tianlei; Yang, Chinglai; Jiang, Shibo; Lu, Lu.
  • Sun Z; Key Laboratory of Medical Molecular Virology of MOE/MOH, School of Basic Medical Sciences and Shanghai Public Health Clinical Center, Fudan University, Shanghai 200032, China.
  • Zhu Y; National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
  • Wang Q; Key Laboratory of Medical Molecular Virology of MOE/MOH, School of Basic Medical Sciences and Shanghai Public Health Clinical Center, Fudan University, Shanghai 200032, China.
  • Ye L; Department of Microbiology and Immunology and Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA.
  • Dai Y; Key Laboratory of Medical Molecular Virology of MOE/MOH, School of Basic Medical Sciences and Shanghai Public Health Clinical Center, Fudan University, Shanghai 200032, China.
  • Su S; Key Laboratory of Medical Molecular Virology of MOE/MOH, School of Basic Medical Sciences and Shanghai Public Health Clinical Center, Fudan University, Shanghai 200032, China.
  • Yu F; Key Laboratory of Medical Molecular Virology of MOE/MOH, School of Basic Medical Sciences and Shanghai Public Health Clinical Center, Fudan University, Shanghai 200032, China.
  • Ying T; Key Laboratory of Medical Molecular Virology of MOE/MOH, School of Basic Medical Sciences and Shanghai Public Health Clinical Center, Fudan University, Shanghai 200032, China.
  • Yang C; Department of Microbiology and Immunology and Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA.
  • Jiang S; Key Laboratory of Medical Molecular Virology of MOE/MOH, School of Basic Medical Sciences and Shanghai Public Health Clinical Center, Fudan University, Shanghai 200032, China.
  • Lu L; Lindsley F. Kimball Research Institute, New York Blood Center, New York, NY 10065, USA.
Emerg Microbes Infect ; 5: e65, 2016 Jun 22.
Article en En | MEDLINE | ID: mdl-27329850
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Anticuerpos Anti-VIH / VIH-1 / Vacunas contra el SIDA / Anticuerpos Neutralizantes / Citotoxicidad Celular Dependiente de Anticuerpos / Epítopos Límite: Animals / Humans Idioma: En Año: 2016 Tipo del documento: Article
Texto completo
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XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Anticuerpos Anti-VIH / VIH-1 / Vacunas contra el SIDA / Anticuerpos Neutralizantes / Citotoxicidad Celular Dependiente de Anticuerpos / Epítopos Límite: Animals / Humans Idioma: En Año: 2016 Tipo del documento: Article