Repair of Neurological Function in Response to FK506 Through CaN/NFATc1 Pathway Following Traumatic Brain Injury in Rats.

Wu, Qiaoli; Liu, Guodong; Xu, Lixia; Wen, Xiaochang; Cai, Ying; Fan, Weijia; Yao, Xiuhua; Huang, Huiling; Li, Qingguo

Wu, Qiaoli; Liu, Guodong; Xu, Lixia; Wen, Xiaochang; Cai, Ying; Fan, Weijia; Yao, Xiuhua; Huang, Huiling; Li, Qingguo.

Wu Q; Tianjin Key Laboratory of Cerebrovascular and Neurodegenerative Diseases, Tianjin Neurosurgical Institute, Tianjin, 300060, China.
Liu G; Eighth Department, Research Institute of Surgery, Daping Hospital, Third Military Medical University, Chongqing, 400042, China.
Xu L; Tianjin Key Laboratory of Cerebrovascular and Neurodegenerative Diseases, Tianjin Neurosurgical Institute, Tianjin, 300060, China.
Wen X; Logistics University of PAP(People's Armed Police), Tianjin, 300162, China.
Cai Y; Tianjin Key Laboratory of Cerebrovascular and Neurodegenerative Diseases, Tianjin Neurosurgical Institute, Tianjin, 300060, China.
Fan W; Tianjin Key Laboratory of Cerebrovascular and Neurodegenerative Diseases, Tianjin Neurosurgical Institute, Tianjin, 300060, China.
Yao X; Tianjin Key Laboratory of Cerebrovascular and Neurodegenerative Diseases, Tianjin Neurosurgical Institute, Tianjin, 300060, China.
Huang H; Tianjin Key Laboratory of Cerebrovascular and Neurodegenerative Diseases, Tianjin Neurosurgical Institute, Tianjin, 300060, China. huanghuiling@126.com.
Li Q; Department of Neurosurgery, Tianjin Huanhu Hospital, Tianjin, 300060, China. lqg369@126.com.

Neurochem Res ; 41(10): 2810-2818, 2016 Oct.

Article en En | MEDLINE | ID: mdl-27386875

Asunto(s)

Lesiones Traumáticas del Encéfalo/tratamiento farmacológico; Corteza Cerebral/efectos de los fármacos; Fenómenos Fisiológicos del Sistema Nervioso/efectos de los fármacos; Neuronas/efectos de los fármacos; Transducción de Señal/efectos de los fármacos; Tacrolimus/farmacología; Animales; Lesiones Traumáticas del Encéfalo/metabolismo; Calcineurina/metabolismo; Corteza Cerebral/metabolismo; Modelos Animales de Enfermedad; Interferón gamma/metabolismo; Masculino; Factores de Transcripción NFATC/metabolismo; Neuroglía/efectos de los fármacos; Neuroglía/metabolismo; Neuronas/metabolismo; Fármacos Neuroprotectores/farmacología; Ratas Sprague-Dawley

Palabras clave

FK506; NFATc1 pathway; Neurological protection; Traumatic brain injury

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Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Corteza Cerebral / Tacrolimus / Lesiones Traumáticas del Encéfalo / Fenómenos Fisiológicos del Sistema Nervioso / Neuronas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2016 Tipo del documento: Article

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