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[Not Available]. / Niveau de preuve du suivi thérapeutique pharmacologique de la teicoplanine.
Boulamery, Audrey; Venisse, Nicolas; Le Guellec, Chantal.
  • Boulamery A; Laboratoire de Pharmacologie Médicale et Clinique, CHU Marseille, Université de la Méditerranée, Marseille, France. Electronic address: audrey.boulamery@univmed.fr.
  • Venisse N; Laboratoire de Toxicologie et Pharmacocinétique, CHU Poitiers, Poitiers, France.
  • Le Guellec C; CHRU de Tours, Université François-Rabelais, Tours, France.
Therapie ; 66(1): 45-50, 2011.
Article en Fr | MEDLINE | ID: mdl-27393464
Teicoplanin is a glycopeptid antibiotic used for treatment of serious infections caused by Gram+ bacteriae. The treatment scheme corresponds to an initial loading dose followed by maintenance dose. High interindividual pharmacokinetic variability and strong relation between high through concentrations, dose and clinical success, support the need of therapeutic drug monitoring using through concentrations. Achieving through concentrations ≥10-15 mg/L or ≥20-40 mg/L, regarding the measurement method and the infection severity, is recommended to increase clinical success rate. The level of proof of therapeutic drug monitoring is evaluated: "necessary".
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Texto completo: 1 Banco de datos: MEDLINE Idioma: Fr Año: 2011 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Idioma: Fr Año: 2011 Tipo del documento: Article