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Infection of laboratory colonies of Anopheles mosquitoes with Plasmodium vivax from cryopreserved clinical isolates.
Shaw-Saliba, Kathryn; Clarke, David; Santos, Jorge M; Menezes, Maria José; Lim, Caeul; Mascarenhas, Anjali; Chery, Laura; Gomes, Edwin; March, Sandra; Bhatia, Sangeeta N; Rathod, Pradipsinh K; Ferreira, Marcelo U; Catteruccia, Flaminia; Duraisingh, Manoj T.
  • Shaw-Saliba K; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
  • Clarke D; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
  • Santos JM; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
  • Menezes MJ; Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
  • Lim C; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
  • Mascarenhas A; Department of Chemistry, University of Washington, Seattle, WA, USA; Department of Medicine, Goa Medical College and Hospital, Bambolim 403202, Goa, India.
  • Chery L; Department of Chemistry, University of Washington, Seattle, WA, USA.
  • Gomes E; Department of Medicine, Goa Medical College and Hospital, Bambolim 403202, Goa, India.
  • March S; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Department of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Bhatia SN; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Department of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Rathod PK; Department of Chemistry, University of Washington, Seattle, WA, USA; Department of Medicine, Goa Medical College and Hospital, Bambolim 403202, Goa, India.
  • Ferreira MU; Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
  • Catteruccia F; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
  • Duraisingh MT; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA. Electronic address: mduraisi@hsph.harvard.edu.
Int J Parasitol ; 46(11): 679-83, 2016 10.
Article en En | MEDLINE | ID: mdl-27456552
ABSTRACT
Plasmodium vivax is the most geographically widespread malaria parasite. Unique features of transmission biology complicate P. vivax control. Interventions targeting transmission are required for malaria eradication. In the absence of an in vitro culture, transmission studies rely on live isolates from non-human primates or endemic regions. Here, we demonstrate P. vivax gametocytes from both India and Brazil are stable during cryopreservation. Importantly, cryopreserved gametocytes from Brazil were capable of infecting three anopheline mosquito species in feedings done in the United States. These findings create new opportunities for transmission studies in diverse locales.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Plasmodium vivax / Criopreservación / Malaria Vivax / Insectos Vectores / Anopheles Límite: Animals / Humans País como asunto: America do sul / Asia / Brasil Idioma: En Año: 2016 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Plasmodium vivax / Criopreservación / Malaria Vivax / Insectos Vectores / Anopheles Límite: Animals / Humans País como asunto: America do sul / Asia / Brasil Idioma: En Año: 2016 Tipo del documento: Article