Cold Spots in Protein Binding.

Shirian, Jason; Sharabi, Oz; Shifman, Julia M

Shirian, Jason; Sharabi, Oz; Shifman, Julia M.

Shirian J; Department of Biological Chemistry, The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.
Sharabi O; Department of Biological Chemistry, The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.
Shifman JM; Department of Biological Chemistry, The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 91904, Israel. Electronic address: jshifman@mail.huji.ac.il.

Trends Biochem Sci ; 41(9): 739-745, 2016 09.

Article en En | MEDLINE | ID: mdl-27477052

Asunto(s)

Proteínas/química; Proteínas/metabolismo; Humanos; Unión Proteica; Ingeniería de Proteínas; Mapeo de Interacción de Proteínas; Proteínas/genética

Palabras clave

binding affinity; binding energetics; binding landscapes; proteinprotein interactions; saturation mutagenesis

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Límite: Humans Idioma: En Año: 2016 Tipo del documento: Article

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Límite: Humans Idioma: En Año: 2016 Tipo del documento: Article