DNA hypermethylation analysis in sputum of asymptomatic subjects at risk for lung cancer participating in the NELSON trial: argument for maximum screening interval of 2âyears.

Hubers, A Jasmijn; Heideman, Daniëlle A M; Duin, Sylvia; Witte, Birgit I; de Koning, Harry J; Groen, Harry J M; Prinsen, Clemens F M; Bolijn, Anne S; Wouters, Mandy; van der Meer, Susanne E; Steenbergen, Renske D M; Snijders, Peter J F; Uyterlinde, Anne; Berkhof, Hans; Smit, Egbert F; Thunnissen, Erik

DNA hypermethylation analysis in sputum of asymptomatic subjects at risk for lung cancer participating in the NELSON trial: argument for maximum screening interval of 2âyears.

Hubers, A Jasmijn; Heideman, Daniëlle A M; Duin, Sylvia; Witte, Birgit I; de Koning, Harry J; Groen, Harry J M; Prinsen, Clemens F M; Bolijn, Anne S; Wouters, Mandy; van der Meer, Susanne E; Steenbergen, Renske D M; Snijders, Peter J F; Uyterlinde, Anne; Berkhof, Hans; Smit, Egbert F; Thunnissen, Erik.

Hubers AJ; Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands.
Heideman DA; Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands.
Duin S; Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands.
Witte BI; Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands.
de Koning HJ; Department of Public Health, Erasmus Medical Center, Rotterdam, The Netherlands.
Groen HJ; Department of Pulmonary Diseases, University Medical Center Groningen, Groningen, The Netherlands.
Prinsen CF; Department of Pathology, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands.
Bolijn AS; Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands.
Wouters M; Department of Pathology, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands.
van der Meer SE; Department of Pathology, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands.
Steenbergen RD; Department of Pathology, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands.
Snijders PJ; Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands.
Uyterlinde A; Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands.
Berkhof H; Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands.
Smit EF; Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands.
Thunnissen E; Department of Pulmonary Diseases, VU University Medical Center, Amsterdam, The Netherlands.

J Clin Pathol ; 70(3): 250-254, 2017 Mar.

Article en En | MEDLINE | ID: mdl-27496969

Asunto(s)

Biomarcadores de Tumor/análisis; Metilación de ADN; Detección Precoz del Cáncer/métodos; Neoplasias Pulmonares/diagnóstico; Esputo/química; Adulto; Anciano; Femenino; Humanos; Masculino; Persona de Mediana Edad; Reacción en Cadena de la Polimerasa; Sensibilidad y Especificidad; Proteínas Supresoras de Tumor/análisis

Palabras clave

LUNG CANCER; ONCOGENES; PCR; SPUTUM

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Esputo / Biomarcadores de Tumor / Metilación de ADN / Detección Precoz del Cáncer / Neoplasias Pulmonares Tipo de estudio: Clinical_trials / Diagnostic_studies / Etiology_studies / Risk_factors_studies / Screening_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Año: 2017 Tipo del documento: Article

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