Evaluation of an Amino Acid-Based Formula in Infants Not Responding to Extensively Hydrolyzed Protein Formula.
J Pediatr Gastroenterol Nutr
; 63(5): 531-533, 2016 11.
Article
en En
| MEDLINE
| ID: mdl-27526059
ABSTRACT
Nearly 2% to 3% of infants and children younger than 3 years have confirmed cow's milk protein allergy with multiple clinical presentations including atopic dermatitis (AD), diarrhea, and vomiting/spitting up. Although most infants with cow's milk protein allergy experience clinical improvement with the use of an extensively hydrolyzed (EH) formula, highly sensitive infants may require an amino acid-based formula. In this observational, prospective study, 30 infants (1-12 months of age) with a history of weight loss and persistent allergic manifestations while on an EH formula were provided an amino acid-based formula for 12 weeks. Mean weight gain (z score change) improved +0.43â±â0.28 (meanâ±âstandard deviation) after the 12-week feeding period. Improvement was observed for many allergic symptoms including significant decreases in AD severity (Pâ=â0.02). These results indicate the new amino acid-based infant formula supported healthy weight gain and improvement in allergic manifestations in infants not responding to EH formulas.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Desarrollo Infantil
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Hipersensibilidad a la Leche
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Fórmulas Infantiles
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Aminoácidos
Tipo de estudio:
Observational_studies
Límite:
Female
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Humans
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Infant
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Male
Idioma:
En
Año:
2016
Tipo del documento:
Article