IgM Memory Cells: First Responders in Malaria.
Immunity
; 45(2): 235-7, 2016 08 16.
Article
en En
| MEDLINE
| ID: mdl-27533010
ABSTRACT
Following the fate of antigen-specific memory B cells has been difficult. In this issue of Immunity, Krishnamurty et al. (2016) use a novel B cell tetramer to define Plasmodium-specific memory B cells in parasite-infected mice and demonstrate that after re-infection, somatically mutated IgM(+) memory B cells function as first responders by rapidly differentiating into T-cell-dependent plasmablasts and T-cell-independent plasma cells.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Memoria Inmunológica
/
Malaria
Límite:
Animals
Idioma:
En
Año:
2016
Tipo del documento:
Article