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Crystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase That Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate during the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus.
Chang, Chin-Yuan; Lohman, Jeremy R; Cao, Hongnan; Tan, Kemin; Rudolf, Jeffrey D; Ma, Ming; Xu, Weijun; Bingman, Craig A; Yennamalli, Ragothaman M; Bigelow, Lance; Babnigg, Gyorgy; Yan, Xiaohui; Joachimiak, Andrzej; Phillips, George N; Shen, Ben.
  • Chang CY; Department of Chemistry, The Scripps Research Institute , Jupiter, Florida 33458, United States.
  • Lohman JR; Department of Chemistry, The Scripps Research Institute , Jupiter, Florida 33458, United States.
  • Cao H; BioScience at Rice and Department of Chemistry, Rice University , Houston, Texas 77251, United States.
  • Tan K; Midwest Center for Structural Genomics and Structural Biology Center, Biosciences Division, Argonne National Laboratory , Argonne, Illinois 60439, United States.
  • Rudolf JD; Department of Chemistry, The Scripps Research Institute , Jupiter, Florida 33458, United States.
  • Ma M; Department of Chemistry, The Scripps Research Institute , Jupiter, Florida 33458, United States.
  • Xu W; BioScience at Rice and Department of Chemistry, Rice University , Houston, Texas 77251, United States.
  • Bingman CA; Department of Biochemistry, University of Wisconsin-Madison , Madison, Wisconsin 53705, United States.
  • Yennamalli RM; BioScience at Rice and Department of Chemistry, Rice University , Houston, Texas 77251, United States.
  • Bigelow L; Department of Biotechnology and Bioinformatics, Jaypee University of Information Technology , Waknaghat, Himachal Pradesh, India 173234.
  • Babnigg G; Midwest Center for Structural Genomics and Structural Biology Center, Biosciences Division, Argonne National Laboratory , Argonne, Illinois 60439, United States.
  • Yan X; Midwest Center for Structural Genomics and Structural Biology Center, Biosciences Division, Argonne National Laboratory , Argonne, Illinois 60439, United States.
  • Joachimiak A; Department of Chemistry, The Scripps Research Institute , Jupiter, Florida 33458, United States.
  • Phillips GN; Midwest Center for Structural Genomics and Structural Biology Center, Biosciences Division, Argonne National Laboratory , Argonne, Illinois 60439, United States.
  • Shen B; BioScience at Rice and Department of Chemistry, Rice University , Houston, Texas 77251, United States.
Biochemistry ; 55(36): 5142-54, 2016 09 13.
Article en En | MEDLINE | ID: mdl-27560143

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Streptomyces / Sarcoglicanos / Aminoglicósidos / Antibacterianos Límite: Humans Idioma: En Año: 2016 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Streptomyces / Sarcoglicanos / Aminoglicósidos / Antibacterianos Límite: Humans Idioma: En Año: 2016 Tipo del documento: Article