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Structure of the Epigenetic Oncogene MMSET and Inhibition by N-Alkyl Sinefungin Derivatives.
Tisi, Dominic; Chiarparin, Elisabetta; Tamanini, Emiliano; Pathuri, Puja; Coyle, Joseph E; Hold, Adam; Holding, Finn P; Amin, Nader; Martin, Agnes C L; Rich, Sharna J; Berdini, Valerio; Yon, Jeff; Acklam, Paul; Burke, Rosemary; Drouin, Ludovic; Harmer, Jenny E; Jeganathan, Fiona; van Montfort, Rob L M; Newbatt, Yvette; Tortorici, Marcello; Westlake, Maura; Wood, Amy; Hoelder, Swen; Heightman, Tom D.
  • Tisi D; Astex Pharmaceuticals , 436 Cambridge Science Park, Milton Road, Cambridge, United Kingdom CB4 0QA.
  • Chiarparin E; Astex Pharmaceuticals , 436 Cambridge Science Park, Milton Road, Cambridge, United Kingdom CB4 0QA.
  • Tamanini E; Astex Pharmaceuticals , 436 Cambridge Science Park, Milton Road, Cambridge, United Kingdom CB4 0QA.
  • Pathuri P; Astex Pharmaceuticals , 436 Cambridge Science Park, Milton Road, Cambridge, United Kingdom CB4 0QA.
  • Coyle JE; Astex Pharmaceuticals , 436 Cambridge Science Park, Milton Road, Cambridge, United Kingdom CB4 0QA.
  • Hold A; Astex Pharmaceuticals , 436 Cambridge Science Park, Milton Road, Cambridge, United Kingdom CB4 0QA.
  • Holding FP; Astex Pharmaceuticals , 436 Cambridge Science Park, Milton Road, Cambridge, United Kingdom CB4 0QA.
  • Amin N; Astex Pharmaceuticals , 436 Cambridge Science Park, Milton Road, Cambridge, United Kingdom CB4 0QA.
  • Martin AC; Astex Pharmaceuticals , 436 Cambridge Science Park, Milton Road, Cambridge, United Kingdom CB4 0QA.
  • Rich SJ; Astex Pharmaceuticals , 436 Cambridge Science Park, Milton Road, Cambridge, United Kingdom CB4 0QA.
  • Berdini V; Astex Pharmaceuticals , 436 Cambridge Science Park, Milton Road, Cambridge, United Kingdom CB4 0QA.
  • Yon J; Astex Pharmaceuticals , 436 Cambridge Science Park, Milton Road, Cambridge, United Kingdom CB4 0QA.
  • Acklam P; CRUK Cancer Therapeutics Unit, Institute of Cancer Research , 15 Cotswold Road, Belmont, Sutton, Surrey, United Kingdom SM2 5NG.
  • Burke R; CRUK Cancer Therapeutics Unit, Institute of Cancer Research , 15 Cotswold Road, Belmont, Sutton, Surrey, United Kingdom SM2 5NG.
  • Drouin L; CRUK Cancer Therapeutics Unit, Institute of Cancer Research , 15 Cotswold Road, Belmont, Sutton, Surrey, United Kingdom SM2 5NG.
  • Harmer JE; CRUK Cancer Therapeutics Unit, Institute of Cancer Research , 15 Cotswold Road, Belmont, Sutton, Surrey, United Kingdom SM2 5NG.
  • Jeganathan F; CRUK Cancer Therapeutics Unit, Institute of Cancer Research , 15 Cotswold Road, Belmont, Sutton, Surrey, United Kingdom SM2 5NG.
  • van Montfort RL; CRUK Cancer Therapeutics Unit, Institute of Cancer Research , 15 Cotswold Road, Belmont, Sutton, Surrey, United Kingdom SM2 5NG.
  • Newbatt Y; CRUK Cancer Therapeutics Unit, Institute of Cancer Research , 15 Cotswold Road, Belmont, Sutton, Surrey, United Kingdom SM2 5NG.
  • Tortorici M; CRUK Cancer Therapeutics Unit, Institute of Cancer Research , 15 Cotswold Road, Belmont, Sutton, Surrey, United Kingdom SM2 5NG.
  • Westlake M; CRUK Cancer Therapeutics Unit, Institute of Cancer Research , 15 Cotswold Road, Belmont, Sutton, Surrey, United Kingdom SM2 5NG.
  • Wood A; CRUK Cancer Therapeutics Unit, Institute of Cancer Research , 15 Cotswold Road, Belmont, Sutton, Surrey, United Kingdom SM2 5NG.
  • Hoelder S; CRUK Cancer Therapeutics Unit, Institute of Cancer Research , 15 Cotswold Road, Belmont, Sutton, Surrey, United Kingdom SM2 5NG.
  • Heightman TD; Astex Pharmaceuticals , 436 Cambridge Science Park, Milton Road, Cambridge, United Kingdom CB4 0QA.
ACS Chem Biol ; 11(11): 3093-3105, 2016 11 18.
Article en En | MEDLINE | ID: mdl-27571355
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Banco de datos: MEDLINE Asunto principal: Oncogenes / Proteínas Represoras / Adenosina / N-Metiltransferasa de Histona-Lisina / Epigénesis Genética Tipo de estudio: Prognostic_studies Idioma: En Año: 2016 Tipo del documento: Article
Search on Google
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Banco de datos: MEDLINE Asunto principal: Oncogenes / Proteínas Represoras / Adenosina / N-Metiltransferasa de Histona-Lisina / Epigénesis Genética Tipo de estudio: Prognostic_studies Idioma: En Año: 2016 Tipo del documento: Article