A Lanthipeptide-like N-Terminal Leader Region Guides Peptide Epimerization by Radical SAM Epimerases: Implications for RiPP Evolution.

Fuchs, Sebastian W; Lackner, Gerald; Morinaka, Brandon I; Morishita, Yohei; Asai, Teigo; Riniker, Sereina; Piel, Jörn.

Fuchs SW; Institute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zurich, Vladimir-Prelog-Weg 4, 8093, Zurich, Switzerland.
Lackner G; Institute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zurich, Vladimir-Prelog-Weg 4, 8093, Zurich, Switzerland.
Morinaka BI; Institute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zurich, Vladimir-Prelog-Weg 4, 8093, Zurich, Switzerland.
Morishita Y; Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba-yama, Aobaku, Sendai, Japan.
Asai T; Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba-yama, Aobaku, Sendai, Japan.
Riniker S; Laboratory of Physical Chemistry, ETH Zürich, Vladimir-Prelog-Weg 2, 8093, Zurich, Switzerland.
Piel J; Institute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zurich, Vladimir-Prelog-Weg 4, 8093, Zurich, Switzerland. jpiel@ethz.ch.

Angew Chem Int Ed Engl ; 55(40): 12330-3, 2016 09 26.

Article en En | MEDLINE | ID: mdl-27584723