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Circular RNA: a new star in neurological diseases.
Li, Tao-Ran; Jia, Yan-Jie; Wang, Qun; Shao, Xiao-Qiu; Lv, Rui-Juan.
  • Li TR; a Department of Neurology, The First Affiliated Hospital of Zhengzhou University , Zhengzhou University , Zhengzhou , PR. China.
  • Jia YJ; b Department of Neurology, Beijing Tiantan Hospital , Capital Medical University , Beijing , PR. China ; China National Clinical Research Center for Neurological Diseases , Beijing , PR. China.
  • Wang Q; a Department of Neurology, The First Affiliated Hospital of Zhengzhou University , Zhengzhou University , Zhengzhou , PR. China.
  • Shao XQ; b Department of Neurology, Beijing Tiantan Hospital , Capital Medical University , Beijing , PR. China ; China National Clinical Research Center for Neurological Diseases , Beijing , PR. China.
  • Lv RJ; b Department of Neurology, Beijing Tiantan Hospital , Capital Medical University , Beijing , PR. China ; China National Clinical Research Center for Neurological Diseases , Beijing , PR. China.
Int J Neurosci ; 127(8): 726-734, 2017 Aug.
Article en En | MEDLINE | ID: mdl-27619342
ABSTRACT
Circular RNAs (circRNAs) are novel endogenous non-coding RNAs characterized by the presence of a covalent bond linking the 3' and 5' ends generated by backsplicing. In this review, we summarize a number of the latest theories regarding the biogenesis, properties and functions of circRNAs. Specifically, we focus on the advancing characteristics and functions of circRNAs in the brain and neurological diseases. CircRNAs exhibit the characteristics of species conservation, abundance and tissue/developmental-stage-specific expression in the brain. We also describe the relationship between circRNAs and several neurological diseases and highlight their functions in neurological diseases.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: ARN / Enfermedades del Sistema Nervioso Límite: Animals / Humans Idioma: En Año: 2017 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: ARN / Enfermedades del Sistema Nervioso Límite: Animals / Humans Idioma: En Año: 2017 Tipo del documento: Article