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Design, synthesis and biological evaluation of novel non-covalent piperidine-containing peptidyl proteasome inhibitors.
Zhang, Jiankang; Gao, Lixin; Xi, Jianjun; Sheng, Li; Zhao, Yanmei; Xu, Lei; Shao, Yidan; Liu, Shourong; Zhuang, Rangxiao; Zhou, Yubo; Li, Jia.
  • Zhang J; Department of Pharmaceutical Preparation, Hangzhou Xixi Hospital, Hangzhou 310023, Zhejiang Province, China.
  • Gao L; National Center for Drug Screening, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Xi J; Department of Pharmaceutical Preparation, Hangzhou Xixi Hospital, Hangzhou 310023, Zhejiang Province, China.
  • Sheng L; National Center for Drug Screening, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Zhao Y; Department of Pharmaceutical Preparation, Hangzhou Xixi Hospital, Hangzhou 310023, Zhejiang Province, China.
  • Xu L; National Center for Drug Screening, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Shao Y; Department of Pharmaceutical Preparation, Hangzhou Xixi Hospital, Hangzhou 310023, Zhejiang Province, China.
  • Liu S; Department of Pharmaceutical Preparation, Hangzhou Xixi Hospital, Hangzhou 310023, Zhejiang Province, China.
  • Zhuang R; Department of Pharmaceutical Preparation, Hangzhou Xixi Hospital, Hangzhou 310023, Zhejiang Province, China. Electronic address: zhuangrangxiao@sina.com.
  • Zhou Y; National Center for Drug Screening, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China. Electronic address: ybzhou@simm.ac.cn.
  • Li J; National Center for Drug Screening, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China. Electronic address: jli@simm.ac.cn.
Bioorg Med Chem ; 24(23): 6206-6214, 2016 12 01.
Article en En | MEDLINE | ID: mdl-27765408

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Piperidinas / Inhibidores de Proteasoma / Antineoplásicos Límite: Animals / Humans Idioma: En Año: 2016 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Piperidinas / Inhibidores de Proteasoma / Antineoplásicos Límite: Animals / Humans Idioma: En Año: 2016 Tipo del documento: Article