Digital imaging biomarkers feed machine learning for melanoma screening.
Exp Dermatol
; 26(7): 615-618, 2017 07.
Article
en En
| MEDLINE
| ID: mdl-27783441
ABSTRACT
We developed an automated approach for generating quantitative image analysis metrics (imaging biomarkers) that are then analysed with a set of 13 machine learning algorithms to generate an overall risk score that is called a Q-score. These methods were applied to a set of 120 "difficult" dermoscopy images of dysplastic nevi and melanomas that were subsequently excised/classified. This approach yielded 98% sensitivity and 36% specificity for melanoma detection, approaching sensitivity/specificity of expert lesion evaluation. Importantly, we found strong spectral dependence of many imaging biomarkers in blue or red colour channels, suggesting the need to optimize spectral evaluation of pigmented lesions.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Neoplasias Cutáneas
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Biomarcadores de Tumor
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Dermoscopía
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Melanoma
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Nevo Pigmentado
Tipo de estudio:
Diagnostic_studies
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Etiology_studies
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Risk_factors_studies
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Screening_studies
Límite:
Humans
Idioma:
En
Año:
2017
Tipo del documento:
Article