Isolation of a simian immunodeficiency virus from a malbrouck (Chlorocebus cynosuros).
Arch Virol
; 162(2): 543-548, 2017 Feb.
Article
en En
| MEDLINE
| ID: mdl-27804019
ABSTRACT
To investigate the diversity of simian immunodeficiency virus (SIV) among nonhuman primates (NHPs) in Zambia, next-generation sequencing was performed to determine the complete genome sequence of a novel SIV recovered by co-culturing African green monkey (AGM) peripheral blood lymphocytes with human CD4+ T-cell lines. We report the first described SIV (SIVagmMAL-ZMB) from a malbrouck (Chlorocebus cynosuros). SIVagmMAL-ZMB was detected by real-time PCR analysis of splenic RNA in 3.2% (3/94) of AGMs and was undetectable in baboons (0/105). SIVagmMAL-ZMB possessed <80% nucleotide sequence identity to known SIV isolates and was located basally to vervet monkey SIV strains in all phylogenies.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Filogenia
/
ARN Viral
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Síndrome de Inmunodeficiencia Adquirida del Simio
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Virus de la Inmunodeficiencia de los Simios
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Cercopithecinae
Límite:
Animals
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Humans
País como asunto:
Africa
Idioma:
En
Año:
2017
Tipo del documento:
Article