Engineering deacetoxycephalosporin C synthase as a catalyst for the bioconversion of penicillins.

Fan, Keqiang; Lin, Baixue; Tao, Yong; Yang, Keqian

Fan, Keqiang; Lin, Baixue; Tao, Yong; Yang, Keqian.

Fan K; State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, No. 1 West Beichen Road, Beijing, 100101, People's Republic of China.
Lin B; ASCR Key Laboratory of Microbial Physiological and Metabolic Engineering, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, People's Republic of China.
Tao Y; ASCR Key Laboratory of Microbial Physiological and Metabolic Engineering, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, People's Republic of China.
Yang K; State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, No. 1 West Beichen Road, Beijing, 100101, People's Republic of China. yangkq@im.ac.cn.

J Ind Microbiol Biotechnol ; 44(4-5): 705-710, 2017 05.

Article en En | MEDLINE | ID: mdl-27826726

Asunto(s)

Biocatálisis; Cefalosporinas/biosíntesis; Penicilinas/biosíntesis; Cefalosporinas/metabolismo; Escherichia coli/genética; Escherichia coli/metabolismo; Penicilina G/metabolismo; Penicilinas/metabolismo; Especificidad por Sustrato

Palabras clave

7-aminodeacetoxycephalosporanic acid (7-ADCA); Bioconversion; Deacetoxycephalosporin C synthase (DAOCS); Penicillin G; Penicillin expandase

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Penicilinas / Cefalosporinas / Biocatálisis Idioma: En Año: 2017 Tipo del documento: Article

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Penicilinas / Cefalosporinas / Biocatálisis Idioma: En Año: 2017 Tipo del documento: Article