Effectiveness of an exercise programme on physical function in patients discharged from hospital following critical illness: a randomised controlled trial (the REVIVE trial).
Thorax
; 72(7): 594-595, 2017 07.
Article
en En
| MEDLINE
| ID: mdl-27852953
ABSTRACT
OBJECTIVE:
To investigate the effectiveness of a 6-week exercise programme in patients discharged home following critical illness compared with standard care.DESIGN:
Multicentre prospective phase II randomised controlled trial, with blinded outcome assessment after hospital discharge, following the 6-week intervention and at 6â months.PARTICIPANTS:
60 patients (30 per group) aged ≥18â years, mechanically ventilated >96â hours, and not in other rehabilitation, that is, cardiac or pulmonary rehabilitation programmes. Participants in the intervention group completed an individually tailored (personalised) exercise programme. OUTCOMEMEASURES:
Primary outcome measure was SF-36 physical functioning following the intervention. Secondary outcomes included a range of performance-based and patient-reported measures.RESULTS:
Improvements in the primary outcome did not differ significantly between groups (mean difference (95% CI) 3.0 (-2.2 to 8.2), p=0.26). The intervention group showed significant improvement compared with the control group (mean difference (95% CI)) in SF-36 role physical (6.6 (0.73 to 12.5), p=0.03); incremental shuttle walk test (83.1â m (8.3 to 157.9), p=0.03); functional limitations profile (-4.8 (-8.7 to -0.9), p=0.02); self-efficacy to exercise (2.2 (0.8 to 3.7), p=0.01) and readiness to exercise (1.3 (0.8 to 1.9), p<0.001). These improvements were not sustained at 6â months except readiness to exercise. Improvements in all other secondary outcome measures were not significant.CONCLUSIONS:
There was no statistically significant difference in the primary outcome measure of self-reported physical function following this 6-week exercise programme. Secondary outcome results will help inform future studies. TRIAL REGISTRATION NUMBER NCT01463579. (results), https//clinicaltrials.gov/.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Ejercicio Físico
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Enfermedad Crítica
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Terapia por Ejercicio
Tipo de estudio:
Clinical_trials
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Observational_studies
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Prognostic_studies
Límite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Año:
2017
Tipo del documento:
Article