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A systems study reveals concurrent activation of AMPK and mTOR by amino acids.
Dalle Pezze, Piero; Ruf, Stefanie; Sonntag, Annika G; Langelaar-Makkinje, Miriam; Hall, Philip; Heberle, Alexander M; Razquin Navas, Patricia; van Eunen, Karen; Tölle, Regine C; Schwarz, Jennifer J; Wiese, Heike; Warscheid, Bettina; Deitersen, Jana; Stork, Björn; Fäßler, Erik; Schäuble, Sascha; Hahn, Udo; Horvatovich, Peter; Shanley, Daryl P; Thedieck, Kathrin.
  • Dalle Pezze P; Institute for Cell and Molecular Biosciences (ICaMB), Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
  • Ruf S; Centre for Integrated Systems Biology of Ageing and Nutrition, Newcastle University Institute for Ageing, Newcastle upon Tyne NE4 5PL, UK.
  • Sonntag AG; Babraham Institute, Babraham Research Campus, Cambridge CB22 3AT, UK.
  • Langelaar-Makkinje M; Department of Bioinformatics and Molecular Genetics (Faculty of Biology), Institute for Biology 3, Albert-Ludwigs-University Freiburg, 79104 Freiburg, Germany.
  • Hall P; Research Training Group (RTG) 1104, Albert-Ludwigs-University Freiburg, 79104 Freiburg, Germany.
  • Heberle AM; Department of Pediatrics, University of Groningen, University Medical Center Groningen (UMCG), 9713 AV Groningen, The Netherlands.
  • Razquin Navas P; Department of Bioinformatics and Molecular Genetics (Faculty of Biology), Institute for Biology 3, Albert-Ludwigs-University Freiburg, 79104 Freiburg, Germany.
  • van Eunen K; Department of Pediatrics, University of Groningen, University Medical Center Groningen (UMCG), 9713 AV Groningen, The Netherlands.
  • Tölle RC; Institute for Cell and Molecular Biosciences (ICaMB), Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
  • Schwarz JJ; Centre for Integrated Systems Biology of Ageing and Nutrition, Newcastle University Institute for Ageing, Newcastle upon Tyne NE4 5PL, UK.
  • Wiese H; Department of Pediatrics, University of Groningen, University Medical Center Groningen (UMCG), 9713 AV Groningen, The Netherlands.
  • Warscheid B; Department of Pediatrics, University of Groningen, University Medical Center Groningen (UMCG), 9713 AV Groningen, The Netherlands.
  • Deitersen J; Department of Neuroscience, School of Medicine and Health Sciences, Carl von Ossietzky University Oldenburg, 26111 Oldenburg, Germany.
  • Stork B; Department of Pediatrics, University of Groningen, University Medical Center Groningen (UMCG), 9713 AV Groningen, The Netherlands.
  • Fäßler E; Department of Bioinformatics and Molecular Genetics (Faculty of Biology), Institute for Biology 3, Albert-Ludwigs-University Freiburg, 79104 Freiburg, Germany.
  • Schäuble S; Department of Bioinformatics and Molecular Genetics (Faculty of Biology), Institute for Biology 3, Albert-Ludwigs-University Freiburg, 79104 Freiburg, Germany.
  • Hahn U; Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg, 79104 Freiburg, Germany.
  • Horvatovich P; Department of Biochemistry and Functional Proteomics, Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany.
  • Shanley DP; Department of Biochemistry and Functional Proteomics, Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany.
  • Thedieck K; Institute of Pharmacology and Toxicology, University of Ulm, 89081 Ulm, Germany.
Nat Commun ; 7: 13254, 2016 11 21.
Article en En | MEDLINE | ID: mdl-27869123

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Quinasas Activadas por AMP / Serina-Treonina Quinasas TOR / Diana Mecanicista del Complejo 1 de la Rapamicina / Diana Mecanicista del Complejo 2 de la Rapamicina / Aminoácidos Límite: Humans Idioma: En Año: 2016 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Quinasas Activadas por AMP / Serina-Treonina Quinasas TOR / Diana Mecanicista del Complejo 1 de la Rapamicina / Diana Mecanicista del Complejo 2 de la Rapamicina / Aminoácidos Límite: Humans Idioma: En Año: 2016 Tipo del documento: Article