Your browser doesn't support javascript.
loading
Successful Lung Transplantation From Hepatitis C Positive Donor to Seronegative Recipient.
Khan, B; Singer, L G; Lilly, L B; Chaparro, C; Martinu, T; Juvet, S; Pipkin, M; Waddell, T K; Keshavjee, S; Humar, A; Cypel, M.
  • Khan B; Toronto Lung Transplant Program, University Health Network, University of Toronto, Toronto, Canada.
  • Singer LG; Toronto Lung Transplant Program, University Health Network, University of Toronto, Toronto, Canada.
  • Lilly LB; Toronto Multi-Organ Transplant Program, University of Toronto, Toronto, Canada.
  • Chaparro C; Toronto Lung Transplant Program, University Health Network, University of Toronto, Toronto, Canada.
  • Martinu T; Toronto Lung Transplant Program, University Health Network, University of Toronto, Toronto, Canada.
  • Juvet S; Toronto Lung Transplant Program, University Health Network, University of Toronto, Toronto, Canada.
  • Pipkin M; Toronto Lung Transplant Program, University Health Network, University of Toronto, Toronto, Canada.
  • Waddell TK; Toronto Lung Transplant Program, University Health Network, University of Toronto, Toronto, Canada.
  • Keshavjee S; Toronto Lung Transplant Program, University Health Network, University of Toronto, Toronto, Canada.
  • Humar A; Toronto Multi-Organ Transplant Program, University of Toronto, Toronto, Canada.
  • Cypel M; Toronto Lung Transplant Program, University Health Network, University of Toronto, Toronto, Canada.
Am J Transplant ; 17(4): 1129-1131, 2017 04.
Article en En | MEDLINE | ID: mdl-27873483
ABSTRACT
Lung transplantation using RNA+ hepatitis C (HCV+) donors to seronegative recipients is not currently performed due to the very high risk of transmission. Previous reports have shown poor survival when this practice was applied. The emergence of new direct-acting antiviral drugs (DAA) suggests a high chance of sustained virologic response in immunocompetent patients. We report here successful transplantation of lungs from HCV+ donor to HCV- recipient. The recipient was an HCV- patient with chronic lung allograft dysfunction. Viral transmission occurred early posttransplant but excellent clinical outcomes were observed including elimination of HCV after 12 weeks of treatment using DAAs.
Asunto(s)
Palabras clave
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Donantes de Tejidos / Obtención de Tejidos y Órganos / Trasplante de Pulmón / Hepatitis C / Receptores de Trasplantes / Supervivencia de Injerto Límite: Adult / Humans / Male / Middle aged Idioma: En Año: 2017 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Donantes de Tejidos / Obtención de Tejidos y Órganos / Trasplante de Pulmón / Hepatitis C / Receptores de Trasplantes / Supervivencia de Injerto Límite: Adult / Humans / Male / Middle aged Idioma: En Año: 2017 Tipo del documento: Article