The revival of old antibiotics for treatment of uncomplicated urinary tract infections in the era of antibiotic stewardship.
Curr Opin Urol
; 27(2): 127-132, 2017 03.
Article
en En
| MEDLINE
| ID: mdl-27875349
ABSTRACT
PURPOSE OF REVIEW In the era of increasing antibiotic resistance worldwide, this review highlights the advantages of revival of old antibiotics for treatment of uncomplicated urinary tract infections (uUTIs). RECENT FINDINGS:
Recent studies have shown that these four oral old antibiotics, fosfomycin trometamol, nitrofurantoin, nitroxoline and pivmecillinam, show no increasing antibiotic resistance against uropathogens causing uUTI, are still effective for the treatment of uUTI and exhibit only minimal or no collateral damage as compared with fluoroquinolones or third-generation cephalosporines.SUMMARY:
According to the principles of antibiotic stewardship, the prudent use of antibiotics is needed. Therefore, recent international and national guidelines already favour these old oral antibiotics as first-choice treatment of uUTI. Unfortunately, implementation of these guidelines is still suboptimal.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Infecciones Urinarias
/
Programas de Optimización del Uso de los Antimicrobianos
/
Antibacterianos
Tipo de estudio:
Guideline
Límite:
Humans
Idioma:
En
Año:
2017
Tipo del documento:
Article