Effects of fatty acid synthase inhibitors on lymphatic vessels: an in vitro and in vivo study in a melanoma model.

Bastos, Débora C; Paupert, Jenny; Maillard, Catherine; Seguin, Fabiana; Carvalho, Marco A; Agostini, Michelle; Coletta, Ricardo D; Noël, Agnès; Graner, Edgard

Bastos, Débora C; Paupert, Jenny; Maillard, Catherine; Seguin, Fabiana; Carvalho, Marco A; Agostini, Michelle; Coletta, Ricardo D; Noël, Agnès; Graner, Edgard.

Bastos DC; Department of Oral Diagnosis, School of Dentistry of Piracicaba, State University of Campinas (UNICAMP), Piracicaba, Brazil.
Paupert J; Laboratory of Tumor and Development Biology, Groupe Interdisciplinaire de Génoprotéomique Appliqué-Cancer (GIGA-Cancer), University of Liège, Liège, Belgium.
Maillard C; Laboratory of Tumor and Development Biology, Groupe Interdisciplinaire de Génoprotéomique Appliqué-Cancer (GIGA-Cancer), University of Liège, Liège, Belgium.
Seguin F; Department of Oral Diagnosis, School of Dentistry of Piracicaba, State University of Campinas (UNICAMP), Piracicaba, Brazil.
Carvalho MA; Department of Oral Diagnosis, School of Dentistry of Piracicaba, State University of Campinas (UNICAMP), Piracicaba, Brazil.
Agostini M; Department of Oral Diagnosis, School of Dentistry of Piracicaba, State University of Campinas (UNICAMP), Piracicaba, Brazil.
Coletta RD; Department of Oral Diagnosis, School of Dentistry of Piracicaba, State University of Campinas (UNICAMP), Piracicaba, Brazil.
Noël A; Laboratory of Tumor and Development Biology, Groupe Interdisciplinaire de Génoprotéomique Appliqué-Cancer (GIGA-Cancer), University of Liège, Liège, Belgium.
Graner E; Department of Oral Diagnosis, School of Dentistry of Piracicaba, State University of Campinas (UNICAMP), Piracicaba, Brazil.

Lab Invest ; 97(2): 194-206, 2017 02.

Article en En | MEDLINE | ID: mdl-27918556

Asunto(s)

Cerulenina/farmacología; Ácido Graso Sintasas/antagonistas & inhibidores; Lactonas/farmacología; Vasos Linfáticos/efectos de los fármacos; Melanoma Experimental/prevención & control; Animales; Apoptosis/efectos de los fármacos; Western Blotting; Línea Celular; Línea Celular Tumoral; Movimiento Celular/efectos de los fármacos; Proliferación Celular/efectos de los fármacos; Supervivencia Celular/efectos de los fármacos; Ácido Graso Sintasas/genética; Ácido Graso Sintasas/metabolismo; Inhibidores de la Síntesis de Ácidos Grasos/farmacología; Humanos; Linfangiogénesis/efectos de los fármacos; Metástasis Linfática; Vasos Linfáticos/metabolismo; Melanoma/genética; Melanoma/metabolismo; Melanoma/patología; Melanoma Experimental/genética; Melanoma Experimental/metabolismo; Ratones Endogámicos BALB C; Ratones Endogámicos C57BL; Orlistat; Interferencia de ARN; Reacción en Cadena de la Polimerasa de Transcriptasa Inversa; Factor C de Crecimiento Endotelial Vascular/metabolismo; Factor D de Crecimiento Endotelial Vascular/metabolismo

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Melanoma Experimental / Cerulenina / Vasos Linfáticos / Ácido Graso Sintasas / Lactonas Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2017 Tipo del documento: Article

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