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ZEB1-induced tumourigenesis requires senescence inhibition via activation of DKK1/mutant p53/Mdm2/CtBP and repression of macroH2A1.
de Barrios, Oriol; Gyorffy, Balázs; Fernández-Aceñero, María Jesús; Sánchez-Tilló, Ester; Sánchez-Moral, Lidia; Siles, Laura; Esteve-Arenys, Anna; Roué, Gaël; Casal, José I; Darling, Douglas S; Castells, Antoni; Postigo, Antonio.
  • de Barrios O; Group of Transcriptional Regulation of Gene Expression, Department of Oncology and Hematology, IDIBAPS, Barcelona, Spain.
  • Gyorffy B; Lendület Cancer Biomarker Research Group, MTA TTK and 2nd Department of Pediatrics, Semmelweis University, Budapest, Hungary.
  • Fernández-Aceñero MJ; Department of Pathology, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain.
  • Sánchez-Tilló E; Department of Pathology, Hospital Clínico San Carlos, Madrid, Spain.
  • Sánchez-Moral L; Group of Transcriptional Regulation of Gene Expression, Department of Oncology and Hematology, IDIBAPS, Barcelona, Spain.
  • Siles L; Group of Transcriptional Regulation of Gene Expression, Department of Oncology and Hematology, IDIBAPS, Barcelona, Spain.
  • Esteve-Arenys A; Group of Transcriptional Regulation of Gene Expression, Department of Oncology and Hematology, IDIBAPS, Barcelona, Spain.
  • Roué G; Lymphoma Group, Department of Oncology and Hematology, IDIBAPS, Barcelona, Spain.
  • Casal JI; Lymphoma Group, Department of Oncology and Hematology, IDIBAPS, Barcelona, Spain.
  • Darling DS; Department of Cellular and Molecular Medicine, Centro de Investigaciones Biológicas (CIB-CSIC), Madrid, Spain.
  • Castells A; Department of Oral Immunology and Infectious Diseases and Center for Genetics and Molecular Medicine, University of Louisville, Louisville, Kentucky, USA.
  • Postigo A; Institute of Metabolic and Digestive Diseases, Hospital Clínic, Barcelona, Spain.
Gut ; 66(4): 666-682, 2017 04.
Article en En | MEDLINE | ID: mdl-27965283

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Histonas / Neoplasias del Colon / Péptidos y Proteínas de Señalización Intercelular / Carcinogénesis / Homeobox 1 de Unión a la E-Box con Dedos de Zinc Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2017 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Histonas / Neoplasias del Colon / Péptidos y Proteínas de Señalización Intercelular / Carcinogénesis / Homeobox 1 de Unión a la E-Box con Dedos de Zinc Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2017 Tipo del documento: Article