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The Ontario Neurodegenerative Disease Research Initiative (ONDRI).
Farhan, Sali M K; Bartha, Robert; Black, Sandra E; Corbett, Dale; Finger, Elizabeth; Freedman, Morris; Greenberg, Barry; Grimes, David A; Hegele, Robert A; Hudson, Chris; Kleinstiver, Peter W; Lang, Anthony E; Masellis, Mario; McIlroy, William E; McLaughlin, Paula M; Montero-Odasso, Manuel; Munoz, David G; Munoz, Douglas P; Strother, Stephen; Swartz, Richard H; Symons, Sean; Tartaglia, Maria Carmela; Zinman, Lorne; Strong, Michael J.
  • Farhan SM; 1Department of Biochemistry,Schulich School of Medicine & Dentistry,Western University,London,Canada.
  • Bartha R; 2Robarts Research Institute,Western University,London,Canada.
  • Black SE; 4Department of Medicine (Neurology),Sunnybrook Health Sciences Centre,LC Campbell Cognitive Neurology Research Unit,Hurvitz Brain Science Research Program,Sunnybrook Research Institute,University of Toronto,Toronto,Canada.
  • Corbett D; 6Department of Cellular and Molecular Medicine, Faculty of Medicine,University of Ottawa,Ottawa,Canada.
  • Finger E; 7Department of Clinical Neurological Sciences,Schulich School of Medicine & Dentistry,Western University,London,Canada.
  • Freedman M; 8Department of Medicine (Neurology),Baycrest Health Sciences and University of Toronto,Toronto,Ontario,Canada.
  • Greenberg B; 10Toronto Dementia Research Alliance,University Health Network,Toronto,Canada.
  • Grimes DA; 11Department of Medicine,The Ottawa Hospital, Faculty of Medicine,University of Ottawa,Ottawa,Canada.
  • Hegele RA; 1Department of Biochemistry,Schulich School of Medicine & Dentistry,Western University,London,Canada.
  • Hudson C; 12School of Optometry & Vision Science,University of Waterloo,Waterloo,Canada.
  • Kleinstiver PW; 13Schulich School of Medicine & Dentistry,Western University,London,Canada.
  • Lang AE; 14Morton and Gloria Shulman Movement Disorders Clinic and the Edmond J Safra Program in Parkinson's Disease,Toronto Western Hospital and the Department of Medicine,University of Toronto,Toronto,Canada.
  • Masellis M; 4Department of Medicine (Neurology),Sunnybrook Health Sciences Centre,LC Campbell Cognitive Neurology Research Unit,Hurvitz Brain Science Research Program,Sunnybrook Research Institute,University of Toronto,Toronto,Canada.
  • McIlroy WE; 15Department of Kinesiology,University of Waterloo,Waterloo,Canada.
  • McLaughlin PM; 13Schulich School of Medicine & Dentistry,Western University,London,Canada.
  • Montero-Odasso M; 16Gait and Brain Lab,Department of Medicine (Geriatrics) and Epidemiology and Biostatistics,Schulich School of Medicine & Dentistry,London,Canada.
  • Munoz DG; 17Keenan Research Centre for Biomedical Science of St. Michael's Hospital,Laboratory Medicine and Pathobiology,University of Toronto,Division of Pathology,St. Michael's Hospital,Toronto,Canada.
  • Munoz DP; 18Centre for Neuroscience Studies,Queen's University,Kingston,Canada.
  • Strother S; 19Rotman Research Institute,Baycrest,Department of Medical Biophysics,University of Toronto,Toronto,Canada.
  • Swartz RH; 20Department of Medicine (Neurology),L.C. Campbell Cognitive Neurology Research Unit,Hurvitz Brain Science Research Program,Sunnybrook Research Institute,Sunnybrook Health Sciences Centre,Institute of Medical Science, Faculty of Medicine,University of Toronto,Toronto,Canada.
  • Symons S; 21Department of Medical Imaging,Sunnybrook Health Sciences Centre,Toronto,Canada.
  • Tartaglia MC; 22Division of Neurology and Department of Medicine,University of Toronto. Tanz Centre for Research in Neurodegenerative Diseases,University of Toronto,Toronto,Canada.
  • Zinman L; 4Department of Medicine (Neurology),Sunnybrook Health Sciences Centre,LC Campbell Cognitive Neurology Research Unit,Hurvitz Brain Science Research Program,Sunnybrook Research Institute,University of Toronto,Toronto,Canada.
  • Strong MJ; 2Robarts Research Institute,Western University,London,Canada.
Can J Neurol Sci ; 44(2): 196-202, 2017 Mar.
Article en En | MEDLINE | ID: mdl-28003035
ABSTRACT
Because individuals develop dementia as a manifestation of neurodegenerative or neurovascular disorder, there is a need to develop reliable approaches to their identification. We are undertaking an observational study (Ontario Neurodegenerative Disease Research Initiative [ONDRI]) that includes genomics, neuroimaging, and assessments of cognition as well as language, speech, gait, retinal imaging, and eye tracking. Disorders studied include Alzheimer's disease, amyotrophic lateral sclerosis, frontotemporal dementia, Parkinson's disease, and vascular cognitive impairment. Data from ONDRI will be collected into the Brain-CODE database to facilitate correlative analysis. ONDRI will provide a repertoire of endophenotyped individuals that will be a unique, publicly available resource.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedades Neurodegenerativas Tipo de estudio: Observational_studies / Prognostic_studies Límite: Humans País como asunto: America do norte Idioma: En Año: 2017 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedades Neurodegenerativas Tipo de estudio: Observational_studies / Prognostic_studies Límite: Humans País como asunto: America do norte Idioma: En Año: 2017 Tipo del documento: Article