Romidepsin induces G2/M phase arrest via Erk/cdc25C/cdc2/cyclinB pathway and apoptosis induction through JNK/c-Jun/caspase3 pathway in hepatocellular carcinoma cells.
Biochem Pharmacol
; 127: 90-100, 2017 03 01.
Article
en En
| MEDLINE
| ID: mdl-28012958
Palabras clave
5-Fluorouracil (PubChem CID: 3385); Caspase3 pathway; Cdc2; DAPI (PubChem CID: 2954); DMSO (PubChem CID: 679); Erk; Ethanol (PubChem CID: 702); Formaldehyde solution (PubChem CID: 712); G2; Glycine (PubChem CID: 750); Hepatocellular carcinoma; JNK; M phase arrest; Methanol (PubChem CID: 887); Paraformaldehyde (PubChem CID: 123127); Romidepsin; Romidepsin (PubChem CID: 5352062); SB203580 (PubChem CID: 176155); SCH772984 (PubChem CID: 24866313); SP600125 (PubChem CID: 8515); Tween 20 (PubChem CID: 443314); Z-VAD-FMK (PubChem CID: 5497174); c-Jun; cdc25C; cyclinB pathway
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Apoptosis
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Carcinoma Hepatocelular
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Depsipéptidos
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Inhibidores de Histona Desacetilasas
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Puntos de Control de la Fase G2 del Ciclo Celular
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Neoplasias Hepáticas Experimentales
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Antineoplásicos
Límite:
Animals
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Humans
Idioma:
En
Año:
2017
Tipo del documento:
Article