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Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer.
Dey, Prasenjit; Baddour, Joelle; Muller, Florian; Wu, Chia Chin; Wang, Huamin; Liao, Wen-Ting; Lan, Zangdao; Chen, Alina; Gutschner, Tony; Kang, Yaan; Fleming, Jason; Satani, Nikunj; Zhao, Di; Achreja, Abhinav; Yang, Lifeng; Lee, Jiyoon; Chang, Edward; Genovese, Giannicola; Viale, Andrea; Ying, Haoqiang; Draetta, Giulio; Maitra, Anirban; Wang, Y Alan; Nagrath, Deepak; DePinho, Ronald A.
  • Dey P; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
  • Baddour J; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
  • Muller F; Department of Chemical and Biomolecular Engineering, Department of Bioengineering, Rice University, 6100 Main Street, Houston, Texas 77005, USA.
  • Wu CC; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
  • Wang H; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
  • Liao WT; Department of Pathology, Division of Pathology/Lab Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
  • Lan Z; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
  • Chen A; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
  • Gutschner T; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
  • Kang Y; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
  • Fleming J; Department of Surgical Oncology, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
  • Satani N; Department of Surgical Oncology, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
  • Zhao D; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
  • Achreja A; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
  • Yang L; Department of Chemical and Biomolecular Engineering, Department of Bioengineering, Rice University, 6100 Main Street, Houston, Texas 77005, USA.
  • Lee J; Department of Chemical and Biomolecular Engineering, Department of Bioengineering, Rice University, 6100 Main Street, Houston, Texas 77005, USA.
  • Chang E; Department of Chemical and Biomolecular Engineering, Department of Bioengineering, Rice University, 6100 Main Street, Houston, Texas 77005, USA.
  • Genovese G; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
  • Viale A; Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
  • Ying H; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
  • Draetta G; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
  • Maitra A; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
  • Wang YA; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
  • Nagrath D; Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
  • DePinho RA; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
Nature ; 542(7639): 119-123, 2017 02 02.
Article en En | MEDLINE | ID: mdl-28099419
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Eliminación de Gen / Carcinoma Ductal Pancreático / Malato Deshidrogenasa Límite: Animals / Humans / Male Idioma: En Año: 2017 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Eliminación de Gen / Carcinoma Ductal Pancreático / Malato Deshidrogenasa Límite: Animals / Humans / Male Idioma: En Año: 2017 Tipo del documento: Article