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Targeted Fcγ Receptor (FcγR)-mediated Clearance by a Biparatopic Bispecific Antibody.
Kasturirangan, Srinath; Rainey, G Jonah; Xu, Linda; Wang, Xinwei; Portnoff, Alyse; Chen, Tracy; Fazenbaker, Christine; Zhong, Helen; Bee, Jared; Zeng, Zhutian; Jenne, Craig; Wu, Herren; Gao, Changshou.
  • Kasturirangan S; From the Departments of Antibody Discovery and Protein Engineering.
  • Rainey GJ; From the Departments of Antibody Discovery and Protein Engineering.
  • Xu L; From the Departments of Antibody Discovery and Protein Engineering.
  • Wang X; From the Departments of Antibody Discovery and Protein Engineering.
  • Portnoff A; From the Departments of Antibody Discovery and Protein Engineering.
  • Chen T; Oncology, and.
  • Fazenbaker C; Oncology, and.
  • Zhong H; Oncology, and.
  • Bee J; Analytical Biotechnology, Medimmune LLC, Gaithersburg, Maryland 20878 and.
  • Zeng Z; the Department of Microbiology, Immunology and Infectious Diseases, University of Calgary, Calgary, Alberta T2N 4N1, Canada.
  • Jenne C; the Department of Microbiology, Immunology and Infectious Diseases, University of Calgary, Calgary, Alberta T2N 4N1, Canada.
  • Wu H; From the Departments of Antibody Discovery and Protein Engineering.
  • Gao C; From the Departments of Antibody Discovery and Protein Engineering, gaoc@medimmune.com.
J Biol Chem ; 292(10): 4361-4370, 2017 03 10.
Article en En | MEDLINE | ID: mdl-28100773
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Interleucina-6 / Receptores de IgG / Anticuerpos Biespecíficos / Anticuerpos Monoclonales / Complejo Antígeno-Anticuerpo Límite: Animals / Humans Idioma: En Año: 2017 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Interleucina-6 / Receptores de IgG / Anticuerpos Biespecíficos / Anticuerpos Monoclonales / Complejo Antígeno-Anticuerpo Límite: Animals / Humans Idioma: En Año: 2017 Tipo del documento: Article