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LC-MS/MS determination of a human mAb drug candidate in rat serum using an isotopically labeled universal mAb internal standard.
Li, Wenkui; Lin, Hui; Fu, Yunlin; Flarakos, Jimmy.
  • Li W; Department of Drug Metabolism and Pharmacokinetics, Novartis Institutes for BioMedical Research, One Health Plaza, East Hanover, NJ 07936, USA. Electronic address: wenkui.li@novartis.com.
  • Lin H; Department of Drug Metabolism and Pharmacokinetics, Novartis Institutes for BioMedical Research, One Health Plaza, East Hanover, NJ 07936, USA.
  • Fu Y; Department of Drug Metabolism and Pharmacokinetics, Novartis Institutes for BioMedical Research, One Health Plaza, East Hanover, NJ 07936, USA.
  • Flarakos J; Department of Drug Metabolism and Pharmacokinetics, Novartis Institutes for BioMedical Research, One Health Plaza, East Hanover, NJ 07936, USA.
J Chromatogr B Analyt Technol Biomed Life Sci ; 1044-1045: 166-176, 2017 Feb 15.
Article en En | MEDLINE | ID: mdl-28113139
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cromatografía Liquida / Espectrometría de Masas en Tándem / Anticuerpos Monoclonales Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2017 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cromatografía Liquida / Espectrometría de Masas en Tándem / Anticuerpos Monoclonales Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2017 Tipo del documento: Article