Optogenetic inhibition of behavior with anion channelrhodopsins.
Nat Methods
; 14(3): 271-274, 2017 03.
Article
en En
| MEDLINE
| ID: mdl-28114289
ABSTRACT
Optogenetics uses light exposure to manipulate physiology in genetically modified organisms. Abundant tools for optogenetic excitation are available, but the limitations of current optogenetic inhibitors present an obstacle to demonstrating the necessity of neuronal circuits. Here we show that anion channelrhodopsins can be used to specifically and rapidly inhibit neural systems involved in Drosophila locomotion, wing expansion, memory retrieval and gustation, thus demonstrating their broad utility in the circuit analysis of behavior.
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1
Banco de datos:
MEDLINE
Asunto principal:
Rodopsina
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Conducta Animal
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Drosophila
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Optogenética
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Vías Nerviosas
Límite:
Animals
Idioma:
En
Año:
2017
Tipo del documento:
Article