Procalcitonin and Interleukin-6 Levels: Are They Useful Biomarkers in Cardiac Surgery Patients?
Blood Purif
; 43(4): 290-297, 2017.
Article
en En
| MEDLINE
| ID: mdl-28125806
ABSTRACT
BACKGROUND/AIM:
Cardiac surgery-associated acute kidney injury is an independent predictor of chronic renal disease and mortality. The scope of this study was to determine the utility of procalcitonin (PCT) and plasma interleukin-6 (IL-6) levels in predicting renal outcome and mortality in these patients.METHODS:
PCT and plasma IL-6 levels of 122 cardiac surgery patients were measured at 48 h after the surgical procedure. Primary endpoints were adverse renal outcome and mortality. Secondary endpoints were length of stay, bleeding, and number of transfusions.RESULTS:
PCT was found to be a better predictor of adverse renal outcome than IL-6. IL-6 seemed to be a better predictor of both 30-day and overall mortality than PCT. Neither PCT nor IL-6 levels were found to be good predictors of intensive care unit stay and bleeding.CONCLUSION:
PCT may be considered a good predictor of adverse renal outcome in cardiac surgery patients, whereas IL-6 seems to possess a good predictive value for mortality in this population of patients.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Calcitonina
/
Biomarcadores
/
Interleucina-6
/
Lesión Renal Aguda
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Procedimientos Quirúrgicos Cardíacos
Tipo de estudio:
Etiology_studies
/
Prognostic_studies
Límite:
Aged
/
Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Año:
2017
Tipo del documento:
Article