Single molecule detection, thermal fluctuation and life.
Proc Jpn Acad Ser B Phys Biol Sci
; 93(2): 51-63, 2017.
Article
en En
| MEDLINE
| ID: mdl-28190869
ABSTRACT
Single molecule detection has contributed to our understanding of the unique mechanisms of life. Unlike artificial man-made machines, biological molecular machines integrate thermal noises rather than avoid them. For example, single molecule detection has demonstrated that myosin motors undergo biased Brownian motion for stepwise movement and that single protein molecules spontaneously change their conformation, for switching to interactions with other proteins, in response to thermal fluctuation. Thus, molecular machines have flexibility and efficiency not seen in artificial machines.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Temperatura
/
Imagen Individual de Molécula
Tipo de estudio:
Diagnostic_studies
Límite:
Animals
/
Humans
Idioma:
En
Año:
2017
Tipo del documento:
Article