Tolvaptan treatment for severe neonatal autosomal-dominant polycystic kidney disease.
Pediatr Nephrol
; 32(5): 893-896, 2017 05.
Article
en En
| MEDLINE
| ID: mdl-28194574
ABSTRACT
BACKGROUND:
Severe neonatal autosomal-dominant polycystic kidney disease (ADPKD) is rare and easily confused with recessive PKD. Managing such infants is difficult and often unsuccessful. CASE DIAGNOSIS/TREATMENT A female infant with massive renal enlargement, respiratory compromise and hyponatraemia was treated with the arginine vasopressin receptor 2 antagonist tolvaptan. This resolved hyponatraemia, and there was no further increase in renal size.CONCLUSION:
Tolvaptan may be a useful treatment for severe neonatal PKD.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Benzazepinas
/
Riñón Poliquístico Autosómico Dominante
Tipo de estudio:
Etiology_studies
Límite:
Adult
/
Female
/
Humans
/
Newborn
/
Pregnancy
Idioma:
En
Año:
2017
Tipo del documento:
Article