Ligand-induced allostery in the interaction of the <i>Pseudomonas aeruginosa</i> heme binding protein with heme oxygenase.

Deredge, Daniel J; Huang, Weiliang; Hui, Colleen; Matsumura, Hirotoshi; Yue, Zhi; Moënne-Loccoz, Pierre; Shen, Jana; Wintrode, Patrick L; Wilks, Angela

Ligand-induced allostery in the interaction of the Pseudomonas aeruginosa heme binding protein with heme oxygenase.

Deredge, Daniel J; Huang, Weiliang; Hui, Colleen; Matsumura, Hirotoshi; Yue, Zhi; Moënne-Loccoz, Pierre; Shen, Jana; Wintrode, Patrick L; Wilks, Angela.

Deredge DJ; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, MD 21201.
Huang W; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, MD 21201.
Hui C; Institute of Environmental Health, Division of Environmental and Biomolecular Systems, Oregon Health and Science University, Portland, OR 97239.
Matsumura H; Institute of Environmental Health, Division of Environmental and Biomolecular Systems, Oregon Health and Science University, Portland, OR 97239.
Yue Z; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, MD 21201.
Moënne-Loccoz P; Institute of Environmental Health, Division of Environmental and Biomolecular Systems, Oregon Health and Science University, Portland, OR 97239.
Shen J; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, MD 21201.
Wintrode PL; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, MD 21201.
Wilks A; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, MD 21201; awilks@rx.umaryland.edu.

Proc Natl Acad Sci U S A ; 114(13): 3421-3426, 2017 03 28.

Article en En | MEDLINE | ID: mdl-28289188

Asunto(s)

Proteínas Bacterianas/química; Proteínas Bacterianas/metabolismo; Proteínas Portadoras/química; Proteínas Portadoras/metabolismo; Hemo Oxigenasa (Desciclizante)/metabolismo; Hemoproteínas/química; Hemoproteínas/metabolismo; Pseudomonas aeruginosa/metabolismo; Regulación Alostérica; Proteínas Bacterianas/genética; Proteínas Portadoras/genética; Hemo Oxigenasa (Desciclizante)/química; Hemo Oxigenasa (Desciclizante)/genética; Proteínas de Unión al Hemo; Hemoproteínas/genética; Ligandos; Unión Proteica; Estructura Secundaria de Proteína; Pseudomonas aeruginosa/química; Pseudomonas aeruginosa/enzimología; Pseudomonas aeruginosa/genética

Palabras clave

Pseudomonas aeruginosa; allostery; heme binding; heme transfer; proteinprotein interaction

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pseudomonas aeruginosa / Proteínas Bacterianas / Proteínas Portadoras / Hemo Oxigenasa (Desciclizante) / Hemoproteínas Idioma: En Año: 2017 Tipo del documento: Article

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