Effect of immunoglobulin G therapy on serum antibody titers to cytomegalovirus in burn patients.
Am J Surg
; 155(2): 294-7, 1988 Feb.
Article
en En
| MEDLINE
| ID: mdl-2829640
ABSTRACT
We attempted to determine the incidence and significance of cytomegalovirus infection and the effect of immunoglobulin G infusions on specific cytomegalovirus titers in burn patients. On admission, 48 percent of a group of 120 patients (mean burn size 28.5 percent of the total body surface area) were seronegative, including 95 percent of all patients under 20 years of age. Subsequently, 4 of a subgroup of 26 patients (15 percent) had development of a primary infection, and 1 of these patients died from overwhelming bacterial infection. Immunoglobulin G infusion used in the prophylaxis of the septic complications achieved high titers of cytomegalovirus-specific immunoglobulin G, as well as the subsets immunoglobulin G1 and immunoglobulin G3 which are also active against cytomegalovirus.
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Banco de datos:
MEDLINE
Asunto principal:
Infección de Heridas
/
Quemaduras
/
Inmunoglobulina G
/
Infecciones por Citomegalovirus
/
Citomegalovirus
/
Anticuerpos Antivirales
Tipo de estudio:
Clinical_trials
Límite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Año:
1988
Tipo del documento:
Article