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The transcription factor Pax6 is required for pancreatic ß cell identity, glucose-regulated ATP synthesis, and Ca2+ dynamics in adult mice.
Mitchell, Ryan K; Nguyen-Tu, Marie-Sophie; Chabosseau, Pauline; Callingham, Rebecca M; Pullen, Timothy J; Cheung, Rebecca; Leclerc, Isabelle; Hodson, David J; Rutter, Guy A.
  • Mitchell RK; From the Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology, and Metabolism, Imperial College London, Du Cane Road, London W12 0NN, United Kingdom.
  • Nguyen-Tu MS; From the Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology, and Metabolism, Imperial College London, Du Cane Road, London W12 0NN, United Kingdom.
  • Chabosseau P; From the Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology, and Metabolism, Imperial College London, Du Cane Road, London W12 0NN, United Kingdom.
  • Callingham RM; From the Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology, and Metabolism, Imperial College London, Du Cane Road, London W12 0NN, United Kingdom.
  • Pullen TJ; From the Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology, and Metabolism, Imperial College London, Du Cane Road, London W12 0NN, United Kingdom.
  • Cheung R; From the Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology, and Metabolism, Imperial College London, Du Cane Road, London W12 0NN, United Kingdom.
  • Leclerc I; From the Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology, and Metabolism, Imperial College London, Du Cane Road, London W12 0NN, United Kingdom.
  • Hodson DJ; From the Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology, and Metabolism, Imperial College London, Du Cane Road, London W12 0NN, United Kingdom, d.hodson@imperial.ac.uk d.hodson@bham.ac.uk.
  • Rutter GA; the Institute of Metabolism and Systems Research and Centre of Membrane Proteins and Receptors, University of Birmingham, Edgbaston B15 2TT, United Kingdom, and.
J Biol Chem ; 292(21): 8892-8906, 2017 05 26.
Article en En | MEDLINE | ID: mdl-28377501
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Adenosina Trifosfato / Regulación de la Expresión Génica / Calcio / Señalización del Calcio / Células Secretoras de Insulina / Factor de Transcripción PAX6 / Glucosa Límite: Animals / Humans Idioma: En Año: 2017 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Adenosina Trifosfato / Regulación de la Expresión Génica / Calcio / Señalización del Calcio / Células Secretoras de Insulina / Factor de Transcripción PAX6 / Glucosa Límite: Animals / Humans Idioma: En Año: 2017 Tipo del documento: Article