Plasma trans-fatty acid concentrations in fasting adults declined from NHANES 1999-2000 to 2009-2010.
Am J Clin Nutr
; 105(5): 1063-1069, 2017 05.
Article
en En
| MEDLINE
| ID: mdl-28381474
ABSTRACT
Background:
The consumption of trans fatty acids (TFAs) is associated with an increased risk of cardiovascular disease, and reducing their consumption is a major public health objective. Food intake studies have provided estimates for TFA concentrations in the US population; however, there is a need for data on TFA blood concentrations in the population.Objective:
The objective of this study was to determine plasma TFA concentrations in a nationally representative group of fasted adults in the US population in NHANES samples from 1999-2000 and 2009-2010.Design:
Four major TFAs [palmitelaidic acid (C161n-7t), trans vaccenic acid (C181n-7t), elaidic acid (C181n-9t), and linoelaidic acid (C182n-6t,9t)] were measured in plasma in 1613 subjects from NHANES 1999-2000 and 2462 subjects from NHANES 2009-2010 by gas chromatography-mass spectrometry. Geometric means and distribution percentiles were calculated for each TFA and their sum by age, sex, and race/ethnicity (non-Hispanic white, non-Hispanic black, Mexican American), and covariate-adjusted geometric means were computed by using a model that included these demographic and other dietary factors, as well as survey year and any significant interaction terms.Results:
These nationally representative data for the adult US population show that TFA concentrations were 54% lower in NHANES 2009-2010 than in NHANES 1999-2000. Covariate-adjusted geometric means for the sum of the 4 TFAs were 81.4 µmol/L (95% CI 77.3, 85.6 µmol/L) and 37.8 µmol/L (95% CI 36.4, 39.4 µmol/L) in NHANES 1999-2000 and 2009-2010, respectively. Even with the large decline in TFA concentrations, differences between demographic subgroups were comparable in the 2 surveys.Conclusion:
The results indicate an overall reduction in TFA concentrations in the US population and provide a valuable baseline to evaluate the impact of the recent regulation categorizing TFAs as food additives.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Grasas de la Dieta
/
Estado Nutricional
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Ayuno
/
Ácidos Grasos trans
Tipo de estudio:
Etiology_studies
/
Prognostic_studies
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Risk_factors_studies
Límite:
Adult
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Aged
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Aged80
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Female
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Humans
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Male
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Middle aged
País como asunto:
America do norte
Idioma:
En
Año:
2017
Tipo del documento:
Article