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Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase.
Cantor, Jason R; Abu-Remaileh, Monther; Kanarek, Naama; Freinkman, Elizaveta; Gao, Xin; Louissaint, Abner; Lewis, Caroline A; Sabatini, David M.
  • Cantor JR; Department of Biology, Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, 9 Cambridge Center, Cambridge, MA 02142, USA; Department of Biology, Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Koch Institute for Inte
  • Abu-Remaileh M; Department of Biology, Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, 9 Cambridge Center, Cambridge, MA 02142, USA; Department of Biology, Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Koch Institute for Inte
  • Kanarek N; Department of Biology, Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, 9 Cambridge Center, Cambridge, MA 02142, USA; Department of Biology, Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Koch Institute for Inte
  • Freinkman E; Department of Biology, Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, 9 Cambridge Center, Cambridge, MA 02142, USA.
  • Gao X; Department of Biology, Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, 9 Cambridge Center, Cambridge, MA 02142, USA; Beth Israel Deaconess Medical Center, Department of Medicine, Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA.
  • Louissaint A; Massachusetts General Hospital, Department of Pathology, 55 Fruit Street, Boston, MA 02114, USA.
  • Lewis CA; Department of Biology, Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, 9 Cambridge Center, Cambridge, MA 02142, USA.
  • Sabatini DM; Department of Biology, Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, 9 Cambridge Center, Cambridge, MA 02142, USA; Department of Biology, Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Koch Institute for Inte
Cell ; 169(2): 258-272.e17, 2017 Apr 06.
Article en En | MEDLINE | ID: mdl-28388410

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Orotato Fosforribosiltransferasa / Orotidina-5'-Fosfato Descarboxilasa / Ácido Úrico / Medios de Cultivo / Complejos Multienzimáticos Límite: Aged / Animals / Humans / Male / Middle aged Idioma: En Año: 2017 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Orotato Fosforribosiltransferasa / Orotidina-5'-Fosfato Descarboxilasa / Ácido Úrico / Medios de Cultivo / Complejos Multienzimáticos Límite: Aged / Animals / Humans / Male / Middle aged Idioma: En Año: 2017 Tipo del documento: Article