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Transforming growth factor ß-inhibitor Repsox downregulates collagen expression of scleroderma dermal fibroblasts and prevents bleomycin-induced mice skin fibrosis.
Ide, Maho; Jinnin, Masatoshi; Tomizawa, Yukiko; Wang, Zhongzhi; Kajihara, Ikko; Fukushima, Satoshi; Hashizume, Yoshinobu; Asano, Yoshihide; Ihn, Hironobu.
  • Ide M; Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
  • Jinnin M; Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
  • Tomizawa Y; Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
  • Wang Z; Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
  • Kajihara I; Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
  • Fukushima S; Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
  • Hashizume Y; RIKEN Program for Drug Discovery and Medical Technology Platforms, Wako, Saitama, Japan.
  • Asano Y; Department of Dermatology, University of Tokyo Graduate School of Medicine, Bunkyo-ku, Tokyo, Japan.
  • Ihn H; Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
Exp Dermatol ; 26(11): 1139-1143, 2017 11.
Article en En | MEDLINE | ID: mdl-28418584

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pirazoles / Piridinas / Esclerodermia Sistémica / Piel / Fibrosis / Factor de Crecimiento Transformador beta / Colágeno Tipo I Tipo de estudio: Clinical_trials Límite: Animals / Humans Idioma: En Año: 2017 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pirazoles / Piridinas / Esclerodermia Sistémica / Piel / Fibrosis / Factor de Crecimiento Transformador beta / Colágeno Tipo I Tipo de estudio: Clinical_trials Límite: Animals / Humans Idioma: En Año: 2017 Tipo del documento: Article