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The mitochondrial Na+/Ca2+ exchanger is essential for Ca2+ homeostasis and viability.
Luongo, Timothy S; Lambert, Jonathan P; Gross, Polina; Nwokedi, Mary; Lombardi, Alyssa A; Shanmughapriya, Santhanam; Carpenter, April C; Kolmetzky, Devin; Gao, Erhe; van Berlo, Jop H; Tsai, Emily J; Molkentin, Jeffery D; Chen, Xiongwen; Madesh, Muniswamy; Houser, Steven R; Elrod, John W.
  • Luongo TS; Center for Translational Medicine, Department of Pharmacology, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA.
  • Lambert JP; Center for Translational Medicine, Department of Pharmacology, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA.
  • Gross P; Cardiovascular Research Center, Department of Physiology, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA.
  • Nwokedi M; Center for Translational Medicine, Department of Pharmacology, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA.
  • Lombardi AA; Center for Translational Medicine, Department of Pharmacology, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA.
  • Shanmughapriya S; Center for Translational Medicine, Department of Pharmacology, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA.
  • Carpenter AC; Department of Health and Exercise Physiology, Ursinus College, Collegeville, Pennsylvania 19426, USA.
  • Kolmetzky D; Center for Translational Medicine, Department of Pharmacology, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA.
  • Gao E; Center for Translational Medicine, Department of Pharmacology, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA.
  • van Berlo JH; Department of Medicine, University of Minnesota, Minneapolis, Minnesota 55455, USA.
  • Tsai EJ; Division of Cardiology, Department of Medicine, College of Physicians &Surgeons, Columbia University, New York, New York 10032, USA.
  • Molkentin JD; Department of Pediatrics, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Howard Hughes Medical Institute, Cincinnati, Ohio 45229, USA.
  • Chen X; Cardiovascular Research Center, Department of Physiology, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA.
  • Madesh M; Center for Translational Medicine, Department of Pharmacology, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA.
  • Houser SR; Cardiovascular Research Center, Department of Physiology, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA.
  • Elrod JW; Center for Translational Medicine, Department of Pharmacology, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA.
Nature ; 545(7652): 93-97, 2017 05 04.
Article en En | MEDLINE | ID: mdl-28445457

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Calcio / Intercambiador de Sodio-Calcio / Homeostasis / Mitocondrias Límite: Animals / Female / Humans / Male Idioma: En Año: 2017 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Calcio / Intercambiador de Sodio-Calcio / Homeostasis / Mitocondrias Límite: Animals / Female / Humans / Male Idioma: En Año: 2017 Tipo del documento: Article