Redesign of antifungal polyene glycosylation: engineered biosynthesis of disaccharide-modified NPP.

Kim, Hye-Jin; Kang, Seung-Hoon; Choi, Si-Sun; Kim, Eung-Soo

Kim, Hye-Jin; Kang, Seung-Hoon; Choi, Si-Sun; Kim, Eung-Soo.

Kim HJ; Department of Biological Engineering, Inha University, Incheon, 22212, South Korea.
Kang SH; Department of Biological Engineering, Inha University, Incheon, 22212, South Korea.
Choi SS; Department of Biological Engineering, Inha University, Incheon, 22212, South Korea.
Kim ES; Department of Biological Engineering, Inha University, Incheon, 22212, South Korea. eungsoo@inha.ac.kr.

Appl Microbiol Biotechnol ; 101(12): 5131-5137, 2017 Jun.

Article en En | MEDLINE | ID: mdl-28488115

Asunto(s)

Actinomycetales/metabolismo; Antibacterianos/química; Antifúngicos/química; Disacáridos/metabolismo; Polienos/química; Anfotericina B/química; Antibacterianos/metabolismo; Vías Biosintéticas; Glicosilación; Glicosiltransferasas/metabolismo; Ingeniería Metabólica/métodos; Nistatina/química; Polienos/metabolismo

Palabras clave

Glycosyltransferase; NPP; Polyene; Pseudonocardia

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Polienos / Actinomycetales / Disacáridos / Antibacterianos / Antifúngicos Idioma: En Año: 2017 Tipo del documento: Article

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