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Hexamerization-enhanced CD20 antibody mediates complement-dependent cytotoxicity in serum genetically deficient in C9.
Taylor, Ronald P; Lindorfer, Margaret A; Cook, Erika M; Beurskens, Frank J; Schuurman, Janine; Parren, Paul W H I; Zent, Clive S; VanDerMeid, Karl R; Burack, Richard; Mizuno, Masashi; Morgan, B Paul.
  • Taylor RP; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, USA. Electronic address: rpt@eservices.virginia.edu.
  • Lindorfer MA; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, USA.
  • Cook EM; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, USA.
  • Beurskens FJ; Genmab, The Netherlands.
  • Schuurman J; Genmab, The Netherlands.
  • Parren PWHI; Genmab, The Netherlands; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, The Netherlands.
  • Zent CS; Wilmot Cancer Institute, University of Rochester Medical Center, USA.
  • VanDerMeid KR; Wilmot Cancer Institute, University of Rochester Medical Center, USA.
  • Burack R; Pathology Department, University of Rochester Medical Center, USA.
  • Mizuno M; Nagoya University Graduate School of Medicine, Japan.
  • Morgan BP; Division of Infection & Immunity, School of Medicine, Cardiff University, United Kingdom.
Clin Immunol ; 181: 24-28, 2017 08.
Article en En | MEDLINE | ID: mdl-28578024

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas del Sistema Complemento / Complemento C9 / Leucemia Linfocítica Crónica de Células B / Rituximab / Síndromes de Inmunodeficiencia Límite: Humans Idioma: En Año: 2017 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas del Sistema Complemento / Complemento C9 / Leucemia Linfocítica Crónica de Células B / Rituximab / Síndromes de Inmunodeficiencia Límite: Humans Idioma: En Año: 2017 Tipo del documento: Article